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NCT ID: NCT01592799 Completed - Influenza Clinical Trials

Study on the Burden of Influenza-related Hospitalizations and Emergency Room (ER) Visits in Children in Spain

Start date: November 23, 2010
Phase: N/A
Study type: Interventional

This study aims to quantify the inpatient and ER visits burden of laboratory-confirmed influenza, and compare the clinical features, severity, complications, risk factors and socioeconomic impact of influenza in children presenting with acute respiratory illness (ARI) and/or isolated fever, with or without laboratory-confirmed influenza.

NCT ID: NCT01592786 Completed - Autism Clinical Trials

An Open-Label Safety Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS)

Start date: June 2012
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the safety and tolerability of memantine in pediatric (6-12 years old) patients with autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) and to identify responders for participation in a follow-up randomized withdrawal study.

NCT ID: NCT01592747 Completed - Autism Clinical Trials

Withdrawal Study of Memantine in Pediatric Patients With Autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified Previously Treated With Memantine

Start date: September 2012
Phase: Phase 2
Study type: Interventional

The purpose of this randomized withdrawal study is to evaluate the safety, tolerability, and efficacy of memantine compared with placebo in pediatric patients with autism, Asperger's Disorder, or Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS).

NCT ID: NCT01591824 Completed - Clinical trials for Mechanical Low Back Pain

Study of Effectiveness of Pold in Chronic Nonspecific Low Back Pain

Pold-LBP
Start date: May 2012
Phase: N/A
Study type: Interventional

Through this research is to conduct a pilot clinical trial in the treatment of chronic nonspecific low back pain (degenerative and mechanical), by comparing two groups, one that will apply a technique of physiotherapy by passive movement of the column with oscillations in axial rotation at a frequency of 1.5 to 2 cps (resonance) of low amplitude (called "Pold Concept"), another group that applies the standard protocol of treatment for this condition, as used in the hospital where performed the study. It will compare the levels of efficiency and effectiveness of each treatment and the comparison between them. This will measure the perception of pain intensity and disability.

NCT ID: NCT01591460 Completed - Clinical trials for Hepatitis C, Chronic

A Triple Combination Therapy Study of Boceprevir, Pegasys and Copegus in Previously Untreated Patients With Genotype 1 Chronic Hepatitis C

Start date: August 2012
Phase: Phase 4
Study type: Interventional

This open-label, multicenter, treatment response guided study will evaluate the sustained virological response and safety of the triple combination therapy boceprevir, Pegasys (peginterferon alfa-2a) and Copegus (Ribavirin) in previously untreated patients with genotype 1 chronic hepatitis C. In the lead-in phase, patients will receive a dual combination therapy of Pegasys and Copegus for 4 weeks. In the following triple combination therapy phase, 800 mg boceprevir, 180 mcg Pegasys and 1000-1200 mg Copegus will be administered for 24, 32 or 44 weeks; the duration depending on the patient's treatment response. The anticipated time on study treatment is up to 48 weeks.

NCT ID: NCT01590589 Completed - Huntington Disease Clinical Trials

REGISTRY - an Observational Study of the European Huntington's Disease Network (EHDN)

REGISTRY
Start date: June 2004
Phase: N/A
Study type: Observational

This is a multi-centre, multi-national, prospective, observational study of Huntington's disease (HD) with a control group of volunteers to: - obtain natural history data on many HD mutation carriers and individuals who are part of an HD family - relate phenotypical characteristics (genetic modifiers / wet and dry biomarkers) - expedite identification and recruitment of participants for clinical trials - develop and validate sensitive and reliable outcome measures for detecting onset and change over the natural course of premanifest and manifest HD which may also be potential outcome measures for use in future clinical trials and clinical care - plan for future research studies

NCT ID: NCT01589185 Completed - Clinical trials for Pneumonia Due to Staphylococcus Aureus

Safety, Pharmacokinetics and Efficacy of KBSA301 in Severe Pneumonia (S. Aureus)

Start date: May 2012
Phase: Phase 1/Phase 2
Study type: Interventional

The objectives of this study are to assess the safety, tolerability, pharmacokinetics, pharmacodynamics and clinical outcome of patients who have severe pneumonia caused by Staphylococcus aureus (S. aureus) after a single intravenous administration of KBSA301 in addition of standard of care antibiotic treatment.

NCT ID: NCT01589016 Completed - Ectopic Pregnancies Clinical Trials

Activin A and Inhibin A in Predicting Outcome of Pregnancies of Unknown Location After Assisted Reproductive Technology

Start date: April 2012
Phase: N/A
Study type: Observational

The purpose of this study is to determine the predictive value of a single serum determination of activin A and inhibin A for the prognosis of ectopic pregnancy after in Vitro Fertilization (IVF) cycles, in both native and donated oocytes.

NCT ID: NCT01588496 Completed - Clinical trials for Homozygous Familial Hypercholesterolemia

Trial Evaluating PCSK9 Antibody in Subjects With LDL Receptor Abnormalities

TESLA
Start date: April 5, 2012
Phase: Phase 2/Phase 3
Study type: Interventional

A study to determine the safety, tolerability, and efficacy of evolocumab (AMG 145) in patients with homozygous familial hypercholesterolemia (HoFH).

NCT ID: NCT01588223 Completed - Clinical trials for Endometrial Receptivity Failure

Non Invasive Diagnostic of Endometrial Receptivity

Start date: January 2011
Phase: N/A
Study type: Interventional

The purpose of this study is to determine a lipidomic profile on the endometrial fluid, that can predict endometrial receptivity.