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NCT ID: NCT05236582 Recruiting - Clinical trials for Chemotherapy-induced Thrombocytopenia

Herombopag for Chemotherapy-induced Thrombocytopenia

Start date: March 14, 2022
Phase: Phase 2
Study type: Interventional

To evaluate the efficacy and safety of Herombopag to treat chemotherapy-induced thrombocytopenia in Solid Tumors

NCT ID: NCT05235906 Recruiting - Clinical trials for Gastric Adenocarcinoma

A Phase II Clinical Study of Surufatinib Combined With Sintilimab in the Treatment of Advanced Gastric Cancer

Start date: August 16, 2022
Phase: Phase 2
Study type: Interventional

The efficacy and safety of the use of Surufatinib in combination with Sintilimab.

NCT ID: NCT05235542 Recruiting - Clinical trials for Advanced Malignant Tumors

A Phase Ib/II Study of AK104 and AK117 in Combination With or Without Chemotherapy in Advanced Malignant Tumors

Start date: July 12, 2022
Phase: Phase 1/Phase 2
Study type: Interventional

Phase Ib/II open label, multicenter study to evaluate the efficacy and safety of AK104 (anti-PD-1 and CTLA-4 bispecific antibody) and AK117#AntiCD47 Antibody# combined with or without chemotherapy in advanced malignant tumors

NCT ID: NCT05235516 Recruiting - Clinical trials for Locally Advanced Cervical Carcinoma

A Study of AK104/Placebo Combined With Chemoradiotherapy For The Treatment of Locally Advanced Cervical Cancer

AK104-305
Start date: June 21, 2022
Phase: Phase 3
Study type: Interventional

This study is to evaluate the efficacy and safety of AK104 plus concurrent chemoradiotherapy compared to placebo plus concurrent chemoradiotherapy in participants with locally advanced cervical cancer

NCT ID: NCT05235438 Recruiting - Oncology Clinical Trials

Safety and Toxicity Study of IMM27M in Patients With Advanced Solid Tumor

Start date: June 15, 2022
Phase: Phase 1
Study type: Interventional

This is a single arm, open label, multi-center and fist in human dose escalation study, to evaluate the safety, tolerability, pharmacokinetics and anti-tumor activity in patients with advanced and metastatic solid tumor.

NCT ID: NCT05235412 Recruiting - Breast Feeding Clinical Trials

A Cohort Study on Milk Composition, Health Outcomes, and Feeding Practices of Chinese Mothers and Infants

Phoenix
Start date: November 19, 2021
Phase:
Study type: Observational

This is a cohort study to understand the changes of breastmilk composition in the first six months after birth of Chinese infants.

NCT ID: NCT05235100 Recruiting - Sarcoma,Soft Tissue Clinical Trials

Preoperative IMRT With Concurrent Apatinib for Localised Extremity or Trunk Sarcoma

Start date: September 1, 2021
Phase: Phase 2
Study type: Interventional

To investigate the safety and efficacy of preoperative IMRT and concurrent Apatinib for primary truncal or extremity soft tissue sarcoma; To investigate the Quality of life and extremity function post-combination treatment; To study the mechanism of radio-sensitizing effects of Apatinib for primary truncal or extremity soft tissue sarcoma; To assess the relationship between the MRI imaging, pathological findings and local control.

NCT ID: NCT05235074 Recruiting - Clinical trials for Central Nervous System Tumors

OH2 Oncolytic Viral Therapy in Central Nervous System Tumors

Start date: November 16, 2021
Phase: Phase 1/Phase 2
Study type: Interventional

In the first phase, it mainly explores the safety, tolerability and preliminary effectiveness of two doses of OH2 injection in the treatment of patients with recurrent central nervous system tumors; to evaluate the biodistribution and virus shedding of OH2 injection administered in the tumor cavity; to evaluate the level of anti-HSV2 antibody in patients when OH2 injection is administered intracavitary to tumor; to determine the phase II recommended dose (RP2D) of OH2 injection in the treatment of recurrent glioblastoma. Phase IIa, to evaluate the preliminary efficacy of OH2 injection in the treatment of patients with recurrent glioblastoma after surgery, and to further evaluate the safety of OH2 in the treatment of relapsed glioblastoma.

NCT ID: NCT05234684 Recruiting - Clinical trials for Diffuse Large B Cell Lymphoma (DLBCL)

A Study of Orelabrutinib Plus R-CHOP in Treatment-naïve Patients With MCD Subtype Diffuse Large B-cell Lymphoma

BELIEVE-01
Start date: November 2, 2022
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the safety and efficacy of orelabrutinib combined with R-CHOP regimen versus placebo with R-CHOP in the treatment of treatment-naïve patients with MCD subtype DLBCL.

NCT ID: NCT05233917 Recruiting - Chronic Diseases Clinical Trials

Dietary Metabolic Signatures in Health Study

Start date: May 1, 2018
Phase:
Study type: Observational

The associations between food nutrition and safety factors with the risk of chronic diseases are still unclear. This study is conducted in Jinhua, a city with a high prevalence of chronic diseases in China, to assess relations between food nutrition and safety factors and chronic diseases.