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NCT ID: NCT06175585 Recruiting - Clinical trials for Chronic Kidney Diseases

Construction of Theoretical Model of Medical Treatment Behavior of Patients With Chronic Kidney Disease

Start date: November 29, 2023
Phase:
Study type: Observational

The impact of narrative nursing interventions on negative emotions, self-efficacy, quality of life in individuals undergoing maintenance hemodialysis

NCT ID: NCT06175494 Recruiting - COVID-19 Clinical Trials

A Phase 3 Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of Booster Vaccination With Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell)

Start date: December 19, 2023
Phase: Phase 3
Study type: Interventional

The Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell) developed by WestVac Biopharma Co., Ltd. is a monovalent modified vaccine designed against Omicron XBB.1.5. This is a multi-center, randomized, double-blind, placebo-controlled phase 3 clinical study with two cohorts, i.e. the immuno-bridging observational cohort and the efficacy observational cohort, aims to evaluate the efficacy, safety, and immunogenicity of booster vaccination with Recombinant COVID-19 (XBB) Trimer Protein Vaccine (Sf9 Cell) for the prevention of SARS-CoV-2 infection in a population of 18 years of age and older.

NCT ID: NCT06175455 Recruiting - Long Covid19 Clinical Trials

Diaphragm Dysfunction After COVID-19 as Determined by Dynamic Chest Radiography

DD-COVID-19
Start date: November 10, 2023
Phase:
Study type: Observational

Dynamic chest radiography (DCR) is a rapid and easily performed technique that captures real-time continuous images of the moving chest. COVID-19 has led to various complications and long-term effects, with dyspnea being a common symptom experienced by many patients. Studies conducted abroad have indicated that dyspnea following a new coronavirus infection can be attributed to diaphragm dysfunction. This study using DCR aims to describe diaphragm function in patients after coronavirus disease (COVID-19).

NCT ID: NCT06175351 Recruiting - Clinical trials for Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

Study to Evaluate the Pharmacokinetic Characteristics, Safety, Tolerability, and Preliminary Efficacy of 9MW1911 in Patients With Chronic Obstructive Pulmonary Disease (COPD).

Start date: July 6, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The study will evaluate the pharmacokinetic characteristics, safety, tolerability, and preliminary efficacy of 9MW1911 in combination with standard of care COPD maintenance therapy in patients with moderate to severe COPD.

NCT ID: NCT06174857 Recruiting - Clinical trials for Advanced Non-Small Cell Lung Cancer

Efficacy of Osimertinib in Patients With Lung Cancer

Start date: January 1, 2021
Phase:
Study type: Observational [Patient Registry]

This is a descriptive observational study, in which data are collected in an epidemiological fashion and prospective. This study does not intend to intervene the current medical practice of the recruited patients.

NCT ID: NCT06174597 Recruiting - Clinical trials for Critical Limb Ischemia

Umbilical Cord Artery-derived Perivascular Stem Cells for the Critical Limb Ischemia Therapy

Start date: June 30, 2023
Phase: Early Phase 1
Study type: Interventional

This clinical trial included 2 periods. During the first period, it was a single arm study to explore the safety of umbilical cord artery-derived stem cells (UCA-PSCs) in the treatment of patients with critical limb ischemia (CLI). During the second perid, it was a single-center, randomized, controlled prospective study to determine the efficacy of the UCA-PSCs treatment. Those who had CLI were enrolled in the study.

NCT ID: NCT06174402 Recruiting - Clinical trials for Primary Biliary Cholangitis

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

Start date: August 21, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The main objectives of the study were to assess the effects of fenofibrate on serum alkaline phosphatase, as a composite endpoint and on safety in participants with primary biliary cholangitis (PBC)

NCT ID: NCT06173999 Recruiting - Clinical trials for Peripheral T-cell Lymphoma

A Study of SHR2554 With Chemotherapy in Treatment-naïve Patients With Peripheral T-cell Lymphoma

Start date: December 22, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

The study is being conducted to evaluate the safety and efficacy of SHR2554 with CHOP/CHOEP in treatment- naïve peripheral T-cell lymphoma.

NCT ID: NCT06173986 Recruiting - Clinical trials for Esophageal Squamous Cell Carcinoma

Immunotherapy in Combination With Chemoradiotherapy in Unresectable Locally Advanced Esophageal Cancer

Start date: January 10, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

SCR-ESCC-02 is a multicenter, phase I/II clinical study to investigate the safety and efficacy of induction immunochemotherapy followed by concurrent chemoradiotherapy with anti-PD-1 therapy in patients diagnosed with locally advanced, unresectable esophageal cancer.

NCT ID: NCT06173947 Recruiting - Portal Hypertension Clinical Trials

SSM Predicts Outcomes of CLD Inpatients With Acute Liver Injury

Start date: January 1, 2024
Phase:
Study type: Observational

In this study, a single non-invasive tool, spleen stiffness measurement (SSM), was used to monitor the disease regression of inpatients with chronic liver disease (CLD) and acute liver injury. The present study aimed to establish an early diagnosis warning model for acute-on-chronic liver failure (ACLF) by SSM and investigate the effect of dynamic changes in SSM on the short-term prognosis (28-day, 90-day morbidity and mortality) of inpatients with CLD and acute liver injury.