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NCT ID: NCT00189839 Completed - Clinical trials for Kidney Transplantation

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Kidney Transplantation

Start date: August 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate and to compare the efficacy and safety of a triple modified release tacrolimus FK506E (MR4) / MMF / steroid regimen with a triple standard tacrolimus FK506 / MMF / steroid regimen in patients undergoing kidney transplantation. It shall be demonstrated that FK506E (MR4) is non-inferior to FK506 with regards to the primary endpoint.

NCT ID: NCT00189826 Completed - Clinical trials for Liver Transplantation

A Study to Evaluate the Safety and Efficacy of FK506E (MR4) in Patients Undergoing Primary Liver Transplantation.

Start date: August 2004
Phase: Phase 3
Study type: Interventional

To evaluate and to compare efficacy and safety of a dual regimen with oral modified release tacrolimus FK506E (MR4) / steroids versus a dual regimen with oral tacrolimus FK506 / steroids in patients undergoing primary liver transplantation. It shall be demonstrated that FK506E (MR4) is non-inferior to FK506 with regards to the primary endpoint.

NCT ID: NCT00189735 Completed - Clinical trials for Kidney Transplantation

A Study to Evaluate FK778 in Kidney Transplant Patients

Start date: September 2003
Phase: Phase 2
Study type: Interventional

A dose finding study to evaluate the safety and effectiveness of FK778 in kidney transplant patients

NCT ID: NCT00189618 Completed - Clinical trials for Peripheral Arterial Disease

The Effects of Physical Training, ASA (Aspirin), and Clopidogrel on the Walking Capacity of Patients With Stage II Peripheral Arterial Disease (PAD)

Start date: May 2005
Phase: Phase 4
Study type: Interventional

To evaluate the change in walking capacity after a well organized and structured intensive physical training program with supportive pharmacotherapy with Clopidogrel or ASA. It is hypothesized that statistically superior results will emerge from a structured training supported by Clopidogrel as compared to a structured training supported by ASA.

NCT ID: NCT00189332 Completed - Melanoma Clinical Trials

Use of 852A in Metastatic Cutaneous Melanoma.

Start date: February 2005
Phase: Phase 2
Study type: Interventional

Pilot study to test the efficacy of 852A administered intravenously up to 3 times per week for 12 weeks in subjects with inoperable metastatic cutaneous melanoma.

NCT ID: NCT00185393 Completed - Clinical trials for Lymphoma, Non-Hodgkin

Treatment With [90]Y-Ibritumomab Tiuxetan Versus no Treatment in Patients With Follicular Non Hodgkin Lymphoma (Stage III or IV) Having Achieved a Partial or Complete Remission After First Line Chemotherapy

Start date: August 2001
Phase: Phase 3
Study type: Interventional

The aim of the study is to test [90]Y-ibritumomab tiuxetan, a radioactive antibody, in patients with stage III or IV follicular lymphoma whose disease is in partial or complete remission after first line chemotherapy. The radioactive antibody will be compared with no further treatment to see which is better in the long term after standard lymphoma treatment.

NCT ID: NCT00185211 Completed - Multiple Sclerosis Clinical Trials

BENEFIT Study (Betaferon® / Betaseron® in Newly Emerging Multiple Sclerosis for Initial Treatment) and BENEFIT Follow-up Study

Start date: August 2002
Phase: Phase 3
Study type: Interventional

This study will primarily compare the long-term effects of an early and continued treatment with Betaferon/Betaseron (patients who were treated with active medication during the double-blind BENEFIT study) to treatment initiated either after Clinically Definite Multiple Sclerosis (CDMS) has been diagnosed or after two years (those patients who were treated with placebo during the double-blind BENEFIT study). Analyses are based on the integrated data of the initial BENEFIT study and this follow-up study.

NCT ID: NCT00185172 Completed - Clinical trials for Essential Hypertension

Olmesartan in Essential Hypertension

Start date: January 2002
Phase: Phase 3
Study type: Interventional

To test the efficacy and safety of olmesartan in patients with essential hypertension.

NCT ID: NCT00184795 Completed - Menopause Clinical Trials

Bleed Free Treatment of Menopausal Symptoms With New Ultra Low Dose Hormonal Combinations

CHOICE
Start date: May 28, 2004
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. Postmenopausal women with moderate to severe hot flashes have been recruited into the trial. The earliest effect of ultra low dose HRT (hormone replacement therapy) on frequency and severity of menopausal symptoms, bleeding patterns and safety of different hormonal combinations will be evaluated and compared to placebo over the six month treatment period.

NCT ID: NCT00184678 Completed - Clinical trials for Adult Growth Hormone Deficiency

Effect of Growth Hormone on Bone Mineral Density in Young Adults With Child-hood Onset Growth Hormone Deficiency

Start date: February 2002
Phase: Phase 3
Study type: Interventional

This trial is conducted in Europe. Growth Hormone in young adults with growth hormone deficiency in childhood. This trial compares a treated group of patients with an untreated group of patients.