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NCT ID: NCT04328766 Completed - Clinical trials for Drug-drug Interaction

Pharmacokinetic Interaction Between DWP14012 and DWC202005 in Healthy Volunteers

Start date: September 6, 2020
Phase: Phase 1
Study type: Interventional

An open-label, multiple-dose clinical trial to evaluate the safety/tolerability and pharmacokinetic interaction between DWP14012 and DWC202005 in healthy volunteers

NCT ID: NCT04327206 Completed - COVID-19 Clinical Trials

BCG Vaccination to Protect Healthcare Workers Against COVID-19

BRACE
Start date: March 30, 2020
Phase: Phase 3
Study type: Interventional

Phase III, two-group multicentre, randomised controlled trial in up to 10 078 healthcare workers to determine if BCG vaccination reduces the incidence and severity of COVID-19 during the 2020 pandemic.

NCT ID: NCT04327154 Active, not recruiting - Clinical trials for Digital Nerve Injury

TISSIUM's Nerve Coaptation Device First-in-Human Clinical Trial

Start date: December 16, 2022
Phase: N/A
Study type: Interventional

The purpose of this study is to collect initial safety and device performance data of the TISSIUM's nerve coaptation device for the sutureless repair of digital nerve injuries of the hand in which there has been no substantial loss of nerve tissue. Additional clinical measures that assess device performance, use, and patient reported outcomes will be collected to guide future study design and potential device modifications.

NCT ID: NCT04327024 Completed - Clinical trials for Heart Failure With Preserved Ejection Fraction (HFpEF)

Study of Verinurad in Heart Failure With Preserved Ejection Fraction

AMETHYST
Start date: May 19, 2020
Phase: Phase 2
Study type: Interventional

International, Multicenter, Double-Blind, Placebo and Active Control Efficacy and Safety Study to Evaluate Verinurad combined with Allopurinol in Heart Failure with Preserved Ejection Fraction

NCT ID: NCT04326127 Completed - Sleep Apnea Clinical Trials

Evaluation of Compumedics "Somfit" Device

Start date: November 6, 2019
Phase:
Study type: Observational

To study whether Somfit is substantially equivalent to an existing approved device (i.e. Compumedic's Grael System) to assist in elucidating sleep disorders.

NCT ID: NCT04325022 Recruiting - Clinical trials for Revision of the Hip Joint

Safety and Effectiveness Study of OR3O™ Dual Mobility System in THA

OR3O
Start date: July 27, 2020
Phase:
Study type: Observational

The purpose of this study is to assess the safety and effectiveness of the OR3O™ Dual Mobility System. The study will evaluate the outcome of the Total Hip Arthroplasty using the OR3O™ Dual Mobility System over a ten year period. Survivorship of THA will be assessed up to ten years.

NCT ID: NCT04324814 Completed - Clinical trials for Advanced Solid Tumor

A Trial of SHR-1701 in Subjects With Advanced Solid Tumors

Start date: March 31, 2020
Phase: Phase 1
Study type: Interventional

This is a dose-escalation and dose-expansion Phase 1 trial to evaluate the safety and tolerability of SHR-1701 in subjects with advanced solid tumors.

NCT ID: NCT04323761 Approved for marketing - SARS-CoV2 Infection Clinical Trials

Expanded Access Treatment Protocol: Remdesivir (RDV; GS-5734) for the Treatment of SARS-CoV2 (CoV) Infection (COVID-19)

Start date: n/a
Phase:
Study type: Expanded Access

The primary objective of this study is to provide expanded access of remdesivir (RDV) for the treatment of severe acute respiratory syndrome coronavirus (SARS-CoV2) infection.

NCT ID: NCT04323306 Completed - Malaria Clinical Trials

A Phase 1 Study to Assess the Safety, Tolerability, and Pharmacokinetic Profile of a Single Doses of MMV533.

Start date: August 12, 2020
Phase: Phase 1
Study type: Interventional

Phase 1, single -centre study in 2 parts. The study designs for each part are well established for first-in-human studies and are appropriate to assess safety, tolerability and preliminary pharmacokinetics.

NCT ID: NCT04323098 Active, not recruiting - Hemophilia A Clinical Trials

Study to Evaluate the Efficacy and Safety of Valoctocogene Roxaparvovec, With Prophylactic Steroids in Hemophilia A

GENEr8-3
Start date: December 8, 2020
Phase: Phase 3
Study type: Interventional

This Phase III clinical study will evaluate the safety and effectiveness of valoctocogene roxaparvovec in combination with prophylactic corticosteroids in patients with severe hemophilia A.