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NCT ID: NCT03749161 Recruiting - Cataract Clinical Trials

Low-add Multifocal vs. Monofocal IOLs

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

Compare low-add multifocal IOLs with monofocal IOLs to evaluate if patients in the low-add multifocal IOL group have better unaided distance visual acuity compared to the monofocal group.

NCT ID: NCT03748381 Recruiting - Cataract Clinical Trials

Comparison of 2 Diffractive Trifocal IOLs

Start date: April 1, 2018
Phase: N/A
Study type: Interventional

Compare two commercially available bilateral implanted diffractive trifocal lenses (Zeiss AT Lisa tri vs. Rayner trifocal) after cataract surgery concerning visual function and spectacle independence.

NCT ID: NCT03748368 Recruiting - Cataract Clinical Trials

Computer-based Tutorial for the Informed Consent Process for Cataract Surgery in Turkish or Serbian Speaking Patients

Start date: January 1, 2017
Phase: N/A
Study type: Interventional

Investigate if a computer-based tutorial enhances the quality and efficiency of the informed consent process for cataract surgery in Turkish or Serbian speaking patients.

NCT ID: NCT03745560 Recruiting - Hearing Loss Clinical Trials

Intraoperative EABR for Decision Making

Start date: May 23, 2017
Phase:
Study type: Observational

In this study patients undergoing simultaneous translabyrinthine vestibular schwannoma resection and cochlear implantation are included. The goal of the study is to correlate the eABR results with postoperative hearing results.

NCT ID: NCT03745534 Recruiting - Hearing Loss Clinical Trials

Cochlear Implantation After Gamma Knife Radiosurgery With eABR and Correlation to Postoperative Hearing Results - a Pilot Study

Start date: August 1, 2018
Phase:
Study type: Observational

Patients undergoing cochlear implantation after radio surgery for vestibular schwannoma will be included in the study. Patients will undergo preoperative and intraoperative eABR measurement. Correlations to postoperative hearing results will be drawn.

NCT ID: NCT03740191 Recruiting - Clinical trials for Intermediate Risk Prostate Cancer

Spot-Scanning Based Hypofractionated Proton Therapy for Low and Intermediate Risk Prostate Cancer

Start date: July 3, 2018
Phase: N/A
Study type: Interventional

This prospective study assess the effectiveness and safety of hypofractionated proton radiotherapy in the treatment of intermediate and low risk prostate cancer.

NCT ID: NCT03723642 Recruiting - Appendicitis Acute Clinical Trials

Investigation of Oxidative Stress in Appendectomy - Open Versus Laparoscopic in Childhood and Adolescence

OSAE
Start date: October 2, 2019
Phase: N/A
Study type: Interventional

In the planned prospective randomized study, oxidative stress will be investigated by analyzing volatile organic compounds in the exhaled air in children. Children who have undergone open versus laparoscopic surgery for appendicitis will be compared. A better understanding of the effects of the surgical technique could be a prerequisite for an optimized surgical setting. It could also lead to recommendations for pre- or perioperatively antioxidative agents.

NCT ID: NCT03712644 Recruiting - Clinical trials for Obstructive Coronary Artery Disease

Coronary Revascularization Versus Conservative Therapy in Patients With Treated Critical Limb Ischemia

INCORPORATE
Start date: July 11, 2018
Phase: N/A
Study type: Interventional

The objective of the INCORPORATE trial is to evaluate whether an intentional invasive strategy with ischemia targeted, reasonably complete coronary revascularization and optimal medical therapy is superior as compared to a primary conservative approach and optimal medical therapy alone in terms of spontaneous myocardial infarct-free and overall survival in patients with severe peripheral artery disease, underwent peripheral artery revascularization due to critical limb ischemia. The INCORPORATE trial is designed to be non-blinded, open-label, prospective 1:1 randomized controlled multicentric trial.

NCT ID: NCT03711032 Recruiting - Clinical trials for High-risk Non-muscle Invasive Bladder Cancer

Efficacy and Safety of Pembrolizumab (MK-3475) in Combination With Bacillus Calmette-Guerin (BCG) in High-Risk Non-Muscle Invasive Bladder Cancer (HR NMIBC) (MK-3475-676/KEYNOTE-676)

Start date: December 24, 2018
Phase: Phase 3
Study type: Interventional

This study is designed to assess the antitumor efficacy and safety of pembrolizumab in combination with BCG, compared to BCG monotherapy, in participants with HR NMIBC that is either persistent or recurrent following adequate BCG induction (Cohort A), or that is naïve to BCG treatment (Cohort B). The primary hypothesis for Cohort A is that the combination of pembrolizumab plus BCG has a superior complete response rate (CRR) as assessed by central pathology review compared to BCG in participants with carcinoma in situ (CIS). The primary hypothesis for Cohort B is that the combination of pembrolizumab plus BCG (either reduced maintenance or full maintenance) has a superior Event Free Survival (EFS) compared to BCG.

NCT ID: NCT03707743 Recruiting - Aortic Dissection Clinical Trials

Registry of Patients With Acute/Subacute Type B Aortic Dissection Treated by Means of the STABILISE Technique (STABILISE)

STABILISE
Start date: October 30, 2018
Phase:
Study type: Observational [Patient Registry]

The aim of the study is to evaluate results of patients treated with the STABILISE technique for acute/subacute aortic dissection. Results and postoperative events are reported in accordance with the current reporting standards for endovascular aortic repair prepared and revised by the Ad Hoc Committee for Standardized Reporting Practices in Vascular Surgery of The Society for Vascular Surgery/American Association for Vascular Surgery