Outcomes in Hospitalized Older Patients With COVID-19

Coronavirus Infection Clinical Trial

Official title:

COVIDAge Study- Hospital Des Trois-Chêne

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04385212
• Other study ID #: 2020-00819
• Status: Completed
• Start date: March 13, 2020
• Est. completion date: April 14, 2020

Study information

• Verified date: May 2020
• Source: University Hospital, Geneva
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In December 2019, the first patients infected with the 2019 novel coronavirus (2019-nCoV) were diagnosed in Wuhan. The clinical presentation and course of Severe Acute Respiratory Syndrome-CoV-2 (SARS-CoV-2) infection is poorly understood in older patients and is certainly different from the general population. This project is designed to better understand and to determine clinical, biological and radiological markers of poor adverse outcomes in hospitalized older patients diagnosed with COVID-19.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 230
• Est. completion date: April 14, 2020
• Est. primary completion date: April 14, 2020
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Diagnosis of COVID-19, defined by a positive polymerase chain reaction (PCR) test for SARS-CoV-2 detection, obtained by a nasopharyngeal swab or sputum sample.

• Or patients with negative virus detection in the PCR test, but with a high clinical suspicion will also be considered with COVID-19.

Exclusion Criteria:

• Presence of document indicating a refusal to participate in a research study.

Related Conditions & MeSH terms

• Communicable Diseases
• Coronavirus Infection
• Coronavirus Infections
• Elderly Infection
• Infection
• Old Age; Debility
• Sars-CoV2
• Severe Acute Respiratory Syndrome

Locations

Country	Name	City	State
Switzerland	Department of Rehabilitation and Geriatrics	Geneva

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Geneva

Country where clinical trial is conducted

Switzerland, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	To evaluate the relative contributions of comorbidities on intra-hospitalized death	We measure functional score of comorbidities	1 month
Secondary	To evaluate the relative contributions of functional characteristics on intra-hospitalized death	We measure Functional Independence Measure scale	1 month
Secondary	To explore specific clinical profiles that may influence COVID-19 disease outcomes in the elderly based on geriatrics syndromes	We describe the role fo geriatric syndrome such as delirium, falls	1 month