The Hybrid Combination of CCTA and SPECT and CAG for Evaluation Prognosis of CAD: an Observational Follow-up Study

Coronary Disease Clinical Trial

— HSCA  

Official title:

The First Affiliated Hospital of Nanjing Medical University

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04554134
• Other study ID #: 2019-SR-242
• Secondary ID: BK20141020
• Status: Completed
• Start date: January 1, 2005
• Est. completion date: February 1, 2020

Study information

• Verified date: September 2020
• Source: The First Affiliated Hospital with Nanjing Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

A total of 550 patients with stable angina (40-70% stenosis) tested by coronary CT angiography (CCTA) and single photon emission computed tomography (SPECT) and coronary angiography (CAG) within 3 months were retrospectively recruited from 2005 to 2015 and follow up to 5 years. A new hybrid software was used to analysis the image data.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 550
• Est. completion date: February 1, 2020
• Est. primary completion date: January 1, 2015
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years to 90 Years

Eligibility

Inclusion Criteria:

1. Age: 18-70

2. Gender: All

3. coronary artery disease patients (CAD)

4. underwent CCTA, SPECT and coronary angiography (CAG) together within 3 months

5. Time: 2005-2015

Exclusion Criteria:

1. dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), congenital heart disease (CHD), atrial fibrillation (AF), ventricular tachycardia (VT)

2. Prior coronary revascularization;

3. permanent pacemaker or internal defibrillator

4. prosthetic heart valve

5. coronary image lose

6. coronary artery severe calcification

7. motion artifacts and poor CCTA image quality

Related Conditions & MeSH terms

• Coronary Disease

Locations

Country	Name	City	State
n/a

Sponsors (3)

Lead Sponsor	Collaborator
The First Affiliated Hospital with Nanjing Medical University	Changzhou No.2 People's Hospital, Huai'an First People's Hospital

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Major adverse cardiac events (MACE)	All-cause death, cardiac death, ischemic stroke, unplanned revascularization and nonfatal myocardial infarction	5 YEARS