Drug Coated Balloon Only vs Drug Eluting Stent Angioplasty

Coronary Artery Disease Clinical Trial

Official title: Outcomes of Drug Coated Balloon Angioplasty, A UK Real Life Experience

Status Recruiting

Clinical Trial Summary

Drug coated balloon (DCB) is a relatively new technology which allows the treatment of coronary artery disease without permanent implantation of a metallic scaffold (stent) in the coronary artery. It is recommended by international guidelines for the treatment of in-stent restenosis (i.e. when a previously implanted stent in the coronary artery develops narrowings again). Data on patient outcomes of patients treated with DCB for de novo coronary artery disease (narrowings in artery supplying blood to the heart that has not been previously treated with a stent) are limited to relatively small studies. In our institution, DCBs have been used over the last 10 years and we have developed a large clinical database. We intend to compare the outcomes of all our patients treated clinically with DCB vs patients treated with drug eluting stent (DES). We will, incorporate all patients presenting either with myocardial infarction (heart attack) or stable angina. Our main outcomes will be: Primary 1) mortality Secondary 1) cardiac mortality 2) cardiac rehospitalisation3) composite of cardiac mortality and cardiac rehospitalisation

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Coronary Artery Disease

• NCT number: NCT04482972
• Study type: Observational
• Source: Norfolk and Norwich University Hospitals NHS Foundation Trust
• Contact: Simon C Eccleshall, MRCP, MD
• Phone: 00441603286286
• Email: Simon.eccleshall@nnuh.nhs.uk
• Status: Recruiting
• Start date: September 11, 2017
• Completion date: December 31, 2026