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NCT05242172 Clinical Trial

THE RELATIONSHIP OF CRP/ALBUMIN RATIO LEVEL AND PROGNOSIS IN PREGNANT COVID-19 PATIENTS

Corona Virus Infection Clinical Trial

Official title:
THE RELATIONSHIP OF CRP/ALBUMIN RATIO LEVEL AND PROGNOSIS IN PREGNANT COVID-19 PATIENTS

Clinical Trial Details — Status: Active, not recruiting

Administrative data
NCT number NCT05242172
Other study ID # 14/12/2021-2021/10-19
Secondary ID
Status Active, not recruiting
Phase
First received
Last updated
Start date January 15, 2022
Est. completion date February 28, 2022

Study information
Verified date January 2022
Source Adiyaman University Research Hospital
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The CRP/albumin ratio (CAR) is a recently defined parameter which represents the ratio of a positive acute phase reactant to a negative acute phase reactant. Recent studies have shown that the CRP/albumin ratio is a biomarker with prognostic value for various inflammatory disorders and serious diseases. With this study it is aimed to investigate the effect of CRP/albumin ratio in predicting the severity and prognosis of the disease in pregnant patients with more severe Covid-19 infection.

Description:

Pregnant women are more susceptible to viral infections affecting the respiratory tract than non-pregnant women. Similar to non-pregnant patients, Covid-19 infection occurs with non-specific symptoms in pregnant patients. A computed tomography (CT) scan of lungs and several laboratory parameters are used to predict the prognosis of this infection, which starts with non-specific findings. Although it has been demonstrated that low-dose lung CT can be used safely in pregnant women, both clinicians and pregnant women tend to avoid tomography imaging due to its teratogenic effects The CRP/albumin ratio (CAR) is a recently defined parameter which represents the ratio of a positive acute phase reactant to a negative acute phase reactant. It is an indicator of both the inflammatory state and the nutritional state, simultaneously. Recent studies have shown that the CRP/albumin ratio is a biomarker with prognostic value for various inflammatory disorders and serious diseases. With this study it is aimed to investigate the effect of CRP/albumin ratio in predicting the severity and prognosis of the disease in pregnant patients with more severe Covid-19 infection.

Recruitment information / eligibility
Status Active, not recruiting
Enrollment 127
Est. completion date February 28, 2022
Est. primary completion date February 15, 2022
Accepts healthy volunteers
Gender Female
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: - Covid PCR test positive patients - Pregnant Exclusion Criteria: - Covid PCR test negative - Missed data

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• CRP/Albumin ratio
it is aimed to investigate prognosis and severity of covid-19 infection with using CRP/Albumin ratio in pregnant patient

Locations
Country Name City State
Turkey Adiyaman Training and Research Hospital Adiyaman

Sponsors (1)
Lead Sponsor Collaborator
Adiyaman University Research Hospital

Country where clinical trial is conducted

Turkey, 

Outcome
Type Measure Description Time frame Safety issue
Primary CRP/Albumin ratio First day of hospital stay
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