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Clinical Trial Details — Status: Terminated

Administrative data

NCT number NCT00789646
Other study ID # SI 271/2008
Secondary ID
Status Terminated
Phase N/A
First received
Last updated
Start date June 2008
Est. completion date June 2009

Study information

Verified date March 2019
Source Mahidol University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The propose of this study is to determine the efficacy of 2% xylocaine in reducing pain due to subconjunctival antibiotic and antifungal injection.


Recruitment information / eligibility

Status Terminated
Enrollment 10
Est. completion date June 2009
Est. primary completion date December 2008
Accepts healthy volunteers No
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria:

- The corneal ulcer patients who are diagnosed by ophthalmologist and have 2 of 3 in these following features.

1. corneal epithelial defect with stromal infiltration

2. reaction in anterior chamber

3. positive for bacteria or fungus

- The patients have to receive subconjunctival antibiotic injection twice at least.

- The patients must be informed consent.

Exclusion Criteria:

- The patients who have history of allergy of local anesthetics, antibiotics or antifungal drugs.

- The patients who administered NSAIDs or weak opioids within 24 hours prior to subconjunctival antibiotic/antifungal injection.

- Unable to cooperate with the treatment.

- Pregnant women

Study Design


Related Conditions & MeSH terms


Intervention

Procedure:
Lidocaine/NSS
First injection: subconjunctival 2% lidocaine without adrenaline 0.4 ml. before antibiotic injection Second injection (24 hours later): subconjunctival NSS 0.4 ml. before antibiotic injection
NSS/Lidocaine
First injection: subconjunctival NSS 0.4 ml. before antibiotic injection Second injection (24 hours later): subconjunctival 2% lidocaine without adrenaline 0.4 ml. before antibiotic injection

Locations

Country Name City State
n/a

Sponsors (1)

Lead Sponsor Collaborator
Mahidol University

Outcome

Type Measure Description Time frame Safety issue
Primary Numeric rating scale immediately after injection
Secondary Side effects 24 hours after injection
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