Clinical Trials Logo
  1. Home
  2. Cornea
  3. NCT05745220

Influence of Silicone Hydrogel Contact Lens Neophyte Wear on Corneal Sensitivity — CSCL  

Cornea Clinical Trial

Official title:
Corneal Sensitivity in Silicone Hydrogel Contact Lens Wear

Clinical Trial Summary

Soft contact lenses can affect the ocular surface and sometimes cause intolerance. The aim of this study is to measure corneal sensitivity using the Swiss Liquid Jet aesthesiometer at baseline, after one and after six weeks, in novice daily contact lens wearers.

Clinical Trial Description

Contact lens discomfort is described by many wearers. Wearing contact lenses can influence corneal sensitivity through three mechanisms: hypoxic, mechanical and inflammatory. A change in corneal sensitivity can be considered an indicator of a change in corneal physiology. Corneal sensitivity plays a major role in maintaining eye health. The interest of this study is to test the variability of the corneal sensitivity threshold during a new adaptation of silicone hydrogel contact lenses, and to verify whether there is a correlation with the wearer's comfort. For that, corneal sensitivity threshold measurements are taken at the baseline and then after one and six weeks of daily contact lens wear. The measurement is performed with the Swiss Liquid Jet aesthesiometer for corneal sensitivity (SLACS). After one week and six weeks of daily lens wear, participants complete a Contact Lens Dry Eye Questionnaire (CLDEQ-8) for comfort analysis. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05745220
Study type Interventional
Source University of Applied Sciences and Arts Northwestern Switzerland
Contact
Status Completed
Phase N/A
Start date April 8, 2023
Completion date September 30, 2023
View Details
See also
  Status Clinical Trial Phase
Terminated NCT03674892 - Intranasal Neurostimulation in Ameliorating Symptoms of Neuropathic Corneal Pain N/A
Recruiting NCT04439552 - fMRI and IVCM Cornea Microscopy of CXL in Keratoconus
Not yet recruiting NCT04122651 - Toric Intraocular Lenses for Cataract Patients in the NHS N/A
Recruiting NCT03299530 - Accuracy of Corneal Astigmatism in Different Region Modes
Completed NCT04560790 - Safety and Efficacy of CRISPR/Cas9 mRNA Instantaneous Gene Editing Therapy to Treat Refractory Viral Keratitis N/A
Recruiting NCT03010748 - Multi-center Clinical Trial on Corneal Morphology Analysis in Chinese Population
Completed NCT02293122 - To Investigate Agreement Between the EM-3000 and the Predicate Device Noncon Robo Pachy (F&A) (CellChek XL)
Active, not recruiting NCT06389916 - Euclid Phoenix Lens Design Trial N/A
Completed NCT06353776 - MicroPulse Transscleral Laser Therapy and Its Short-term Impact on Ocular Surface N/A
Completed NCT03906513 - Evaluation of the Efficacy of OMK2 in Recovering Corneal Neural Damage in Patients With Diabetes N/A
Not yet recruiting NCT06392607 - Euclid Phoenix Lens Design Trial 2 N/A
Recruiting NCT05232539 - Efficiency of Intraoperative Optical Coherence Tomography (iOCT) N/A
Completed NCT02781948 - Evaluation of the Repeatability and Reproducibility of Corneal Epithelial Thickness Mapping With iVue SD-OCT N/A
Not yet recruiting NCT05345652 - Evaluation Of Deep Anterior Lamellar Keratoplasty By Anterior Segment Ocular Coherence Tomography
Completed NCT04804592 - Investigation in Corneal Sensation and Contact Lens Wear N/A
Recruiting NCT04626583 - Safety of Locally Delivered Allogeneic Mesenchymal Stromal Cells Phase 1
Recruiting NCT04323358 - Agreement and Accuracy of Different Devices for Biometry Measurements in Patients With Cataract N/A
Completed NCT06277349 - Multifocal-toric IOL Compared to Multifocal IOL Combined With Limbal Relaxing Incisions for Correction of Moderate Astigmatism During Cataract Surgery N/A
Withdrawn NCT02395952 - Healing of Persistent Epithelial Defects N/A
Completed NCT03518775 - Repeatability and Reproducibility of the IOLMaster 700 Vers 1.70 and Agreement With IOLMaster 700 Vers. 1.50 and Pentacam