Home Air Purification for Eosinophilic COPD

Status Enrolling by invitation

Clinical Trial Summary

This study evaluates the influence of home air purification on the lung health of adults with eosinophilic COPD. Half of the participants will receive real air purifiers (HEPA filters) and half will receive sham air purifiers.

Clinical Trial Description

Chronic obstructive pulmonary disease (COPD) is the third most common cause of death in the United States, and is exacerbated by exposure to air pollution. Knowledge about whether air purification affects the health of those with eosinophilic COPD (approximately 40% of all COPD patients seeking care), who generally have more active airway inflammation. If found to be beneficial, home air purification may offer a non-pharmacologic intervention for a large proportion of people with this common and serious disease. This study will evaluate whether home air purification affects lung function, respiratory symptoms, nasal biomarkers (inflammatory proteins and metals) among people with eosinophilic COPD. Participants will be randomized to receive real or sham air purifier in the bedroom and living room for 12 months. The intervention group will receive two high efficiency particulate air (HEPA) air purifiers, while the control group will receive two sham air purifiers that look and sound the same as real HEPA air purifiers. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04252235
Study type	Interventional
Source	Beth Israel Deaconess Medical Center
Contact
Status	Enrolling by invitation
Phase	N/A
Start date	March 15, 2021
Completion date	June 30, 2025

View Details

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