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Chronic Obstructive Pulmonary Disease clinical trials

View clinical trials related to Chronic Obstructive Pulmonary Disease.

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NCT ID: NCT01069289 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Efficacy and Safety Study of Symbicort® Turbuhaler® Versus Oxis® Turbuhaler® in Chronic Obstructive Pulmonary Disease (COPD) Patients

SUMIRE
Start date: January 2010
Phase: Phase 3
Study type: Interventional

The primary purpose of the study is to investigate if Symbicort is more effective than Oxis in increasing forced expiratory volume in one second (FEV1), measured at the clinics, in patients with COPD.

NCT ID: NCT01068613 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Safety and Efficacy of Multiple Doses of QAX028 in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: January 2010
Phase: Phase 2
Study type: Interventional

This study will assess the bronchodilator effects of multiple doses of QAX028 at two different dose levels when compared to tiotropium and placebo in a COPD population.

NCT ID: NCT01068600 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Comparison of Efficacy of Indacaterol Versus Placebo Over 12 Weeks

Start date: January 2010
Phase: Phase 3
Study type: Interventional

This 12-week study evaluated the efficacy and safety of indacaterol versus placebo.

NCT ID: NCT01061970 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Efficacy and Safety of Fispemifene in the Treatment of Hypogonadal Men With Chronic Obstructive Pulmonary Disease That Are on Oral Glucocorticoid Therapy

Start date: January 2007
Phase: Phase 2
Study type: Interventional

The objective of the study is to assess and compare the preliminary efficacy, safety and tolerability of fispemifene 300 mg and placebo given once daily for 4 weeks in the treatment of hypogonadal men with chronic obstructive pulmonary disease (COPD) that are on oral glucocorticoid therapy.

NCT ID: NCT01058499 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Mindfulness Based Stress Reduction in COPD

Start date: February 2010
Phase: Phase 1
Study type: Interventional

The objective of this study is to test the efficacy of a Mindfulness Based Stress Reduction program in COPD on quality of life, dyspnea, daily physical activity and mindfulness during daily life.

NCT ID: NCT01058213 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Nurse Managed Sequential Strength Training and Bicycle Training in Chronic Obstructive Pulmonary Disease (COPD)

Start date: November 2008
Phase: Phase 2
Study type: Interventional

This is a 16 week exercise training program for people with severe to very severe chronic obstructive pulmonary disease (COPD). The purpose of this study is to find out if performing strength training prior to initiating exercise training on a stationary bicycle is associated with greater gains in functional status than bicycle training alone or concurrent bicycle and strength training together.

NCT ID: NCT01057797 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Nurse Managed Upper Body Strength Training in Chronic Obstructive Pulmonary Disease (COPD)

Start date: September 2003
Phase: Phase 2
Study type: Interventional

This is a four month exercise training program for people with chronic obstructive pulmonary disease (COPD)with a 12 month follow-up.

NCT ID: NCT01056081 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Inspiratory Muscle Training in Chronic Obstructive Pulmonary Disease

Start date: April 2006
Phase: Phase 3
Study type: Interventional

Uncertainty persists regarding the usefulness of incorporating inspiratory muscle training (IMT) in pulmonary rehabilitation programs for patients with chronic obstructive pulmonary disease. In this study the investigators investigate whether IMT associated with exercise training would be better than exercise training alone, with regard to exercise capacity, inspiratory muscle strength and dyspnea.

NCT ID: NCT01055405 Completed - COPD Clinical Trials

Study of Sildenafil Effects in Combination With Rehabilitation in Patients With Chronic Obstructive Pulmonary Disease (COPD) and Associated Pulmonary Hypertension

SIL-COPD-02
Start date: August 2008
Phase: Phase 4
Study type: Interventional

Sildenafil is a phosphodiesterase-5 inhibitor that has been approved for the treatment of pulmonary arterial hypertension with orphan drug designation. Sildenafil modulates the nitric oxide (NO) pathway in the vessel wall. Since this pathway is impaired in pulmonary arteries of patients with pulmonary hypertension (PH) associated with chronic obstructive pulmonary disease (COPD), the investigators hypothesized that sildenafil might improve pulmonary hemodynamics and increase exercise tolerance in this condition.

NCT ID: NCT01054170 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease (COPD)

Effect on Structural Changes in Airways, Measured by MSCT, of Twice Daily 60mg AZD9668 for 12 Weeks in Chronic Obstructive Pulmonary Disease (COPD) Patients

Start date: January 2010
Phase: Phase 2
Study type: Interventional

The primary objective of the study is to evaluate structural changes effected by AD9668 in the airways of adults with Chronic Obstructive Pulmonary Disease (COPD) by Multi-Slice Computed Tomography (MSCT)