COPD Exacerbation Clinical Trial
Official title:
Assessment of the Degree of Pneumonia Underdiagnosis in Chronic Obstructive Pulmonary Disease (COPD) Exacerbations Using Chest Low-dose Computed Tomography (CT) and Comparison of Inflammatory Profile Between the Two Entities
* Hypothesis: There is an underdiagnosis of pneumonia in COPD (Chronic Obstructive Pulmonary
Disease) exacerbations which could be demonstrated by performing low-dose chest CT.
Differences in the inflammatory profile in sputum and blood in patients with and without
pneumonia can be seen.
* Objective: To assess the degree of underdiagnosis of pneumonia in COPD exacerbations,
using chest low-dose CT and to compare clinical and inflammatory differences in blood and
sputum between patients with and without pneumonia.
*Material and Methods: Prospective observational study including 75 patients with the
diagnosis of COPD at the time of an exacerbation and with criteria for a respiratory tract
infection. At the time of inclusion clinical features, blood and sputum analysis, chest
X-ray and chest low-dose CT are performed. The investigators divide the patients into two
groups according to the existence of pneumonia and the inflammatory pattern in blood
(inflammatory markers) and sputum (cell populations and inflammatory markers) is compared
between the two branches.
n/a
Observational Model: Case Control, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Active, not recruiting |
NCT06000696 -
Healthy at Home Pilot
|
||
| Recruiting |
NCT03250000 -
Changes in Microcirculation and Functional Status During Exacerbation of COPD
|
N/A | |
| Recruiting |
NCT04142827 -
The Effect of Long Term Therapy With High Flow Humidification Compared to Usual Care in Patients With Bronchiectasis (BX)
|
N/A | |
| Recruiting |
NCT05865184 -
Evaluation of Home-based Sensor System to Detect Health Decompensation in Elderly Patients With History of CHF or COPD
|
||
| Completed |
NCT01892566 -
Using Mobile Health to Respond Early to Acute Exacerbations of COPD in HIV
|
N/A | |
| Completed |
NCT04119856 -
Outgoing Lung Team - a Cross-sectorial Intervention in Patients With COPD
|
N/A | |
| Recruiting |
NCT06118632 -
Physiological and Environmental Data in a Remote Setting to Predict Exacerbation Events in Patients With Chronic Obstructive Pulmonary Disease
|
||
| Recruiting |
NCT04860375 -
Multidisciplinary Management of Severe COPD
|
N/A | |
| Completed |
NCT04170361 -
The Effect of Incentive Spirometry Added to Routine Physiotherapy Program on Hemodynamic Responses and Hospital Stay in Patients With COPD Exacerbation
|
N/A | |
| Not yet recruiting |
NCT03696563 -
FreeO2 PreHospital - Automated Oxygen Titration vs Manual Titration According to the BLS-PCS
|
N/A | |
| Not yet recruiting |
NCT03296215 -
Pattern of Admitted Cases in Respiratory Intensive Care Unit at Assiut University Hospitals
|
N/A | |
| Completed |
NCT03003702 -
Domiciliary Monitoring to Predict Exacerbations of COPD
|
N/A | |
| Completed |
NCT02912689 -
NIV - NAVA vs NIV - PS for COPD Exacerbation
|
N/A | |
| Completed |
NCT01443845 -
Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting β2-agonist (LABA) and Inhaled Corticosteroid (ICS)
|
Phase 4 | |
| Recruiting |
NCT02065921 -
Swiss Chronic Obstructive Pulmonary Disease (COPD) Management Cohort
|
||
| Completed |
NCT04880486 -
Weight Training With VR in Out-Patients With Acute Exacerbation of Chronic Obstructive Pulmonary Disease
|
N/A | |
| Recruiting |
NCT03286127 -
Palliative Outcome Evaluation Muenster I
|
||
| Recruiting |
NCT04638920 -
Molecular Breath Print of COPD Patients With Exacerbations Despite Triple Inhalational Therapy
|
||
| Not yet recruiting |
NCT05897125 -
Telehealth Education Leveraging Electronic Transitions Of Care for COPD Patients
|
N/A | |
| Recruiting |
NCT06304207 -
Telehealth and Onsite Maintenance Exercise in COPD
|
N/A |