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Contraception clinical trials

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NCT ID: NCT03733678 Active, not recruiting - Contraception Clinical Trials

A Randomized-Controlled Trial to Increase the Uptake of LARCs in Cameroon

HGOPY
Start date: March 23, 2021
Phase: N/A
Study type: Interventional

Cameroon exhibits a high and non-decreasing level of maternal mortality (roughly 600 per 100,000 live births), partially related to its relatively high total fertility rate (roughly 4.6). Survey evidence furthermore suggests that a significant fraction of these pregnancies is unwanted or considered mistimed by the mother, especially among females aged 15-19. Despite this, the rate of utilization of family planning (FP) is low: e.g. only 48% of sexually active unmarried women use any form of (modern) contraception, or MC, and even then, it is primarily condoms. The use of LARCs (long-acting reversible contraceptives, i.e. the IUD and implant) is less than 1% according to the most recent Demographic Health Survey. The study investigators propose to use an integrated behavioral science approach to increase the take-up of both SARCs (short-acting reversible contraceptives, i.e. the pill and injectable) and especially LARCs among reproductive-age females in Cameroon, including adolescents who may be unmarried and/or nulliparous. In addition to decreasing maternal mortality and undesired pregnancies, indirect effects for the community will include: increased welfare from reduced side effects that arise due to current one-size-fits-all FP counseling; healthier children due to improved birth spacing; and increased human capital formation both for children and for young (often school-aged) potential mothers. The study investigators propose to conduct the study at HGOPY for a duration of 12 months. The study investigators will provide tablets to each of five nurses that conduct FP counseling to participants at the hospital. The tablets contain a counseling "app" (or decision-support tool or a job-aid) that was jointly developed by professionals from HGOPY, the World Bank, and the Ministry of Health. The study investigators propose an individually-randomized experiment, where the participants will be offered randomly varying discounts for the modern contraceptive methods they wish to adopt. The study investigators also propose to experiment with certain aspects of the "app" to improve its effectiveness - both for the participant and for the nurse. More details on the experimental design are provided below.

NCT ID: NCT03519685 Active, not recruiting - Contraception Clinical Trials

UCSF College Health Study on Contraceptive Training and Education at Community Colleges

Start date: April 9, 2018
Phase: N/A
Study type: Interventional

The purpose of this study is to measure whether a training and education intervention for clinic staff and young women aged 18-25 on contraceptive methods, including intrauterine devices (IUDs) and the implant, will result in greater contraceptive knowledge and access among students in community colleges.

NCT ID: NCT03433911 Active, not recruiting - Contraception Clinical Trials

FemBloc® Permanent Contraception - Early Pivotal Trial

BLOC
Start date: February 2, 2018
Phase: N/A
Study type: Interventional

Prospective, multi-center, international, non-randomized, two-arm study of subjects undergoing either FemBloc or laparoscopic bilateral tubal sterilization (Control). The FemBloc group total study duration will be approximately 65 months. The laparoscopic tubal sterilization (Control) group total study duration will be approximately 62 months.

NCT ID: NCT03187392 Active, not recruiting - Contraception Clinical Trials

Pain Relief for Birth Control Implants Insertion

Start date: June 12, 2017
Phase: Phase 3
Study type: Interventional

The aim of our study is to compare the analgesic effect of topical application of lidocaine-prilocaine cream and lidocaine infiltration during insertion of birth control implants

NCT ID: NCT03127722 Active, not recruiting - Contraception Clinical Trials

Study to Assess Outcomes in Women Undergoing Either Hysteroscopic Sterilization (Essure®) or Laparoscopic Tubal Sterilization

Start date: May 3, 2017
Phase: N/A
Study type: Interventional

This study is designed to assess post-procedural outcomes for women who chose to undergo either hysteroscopic sterilization (Essure®) or laparoscopic tubal sterilization, including: - Pelvic and/or lower abdominal pain - Abnormal uterine bleeding - Surgical intervention (including "insert removal" and hysterectomy) - Allergic, hypersensitivity, or autoimmune-like reactions

NCT ID: NCT02714686 Active, not recruiting - Contraception Clinical Trials

Evaluation of a Mass Media Family Planning Campaign on the Uptake of Contraceptive Methods in Burkina Faso

Start date: April 2016
Phase: N/A
Study type: Interventional

In this experiment, the investigators will study the effect of a mass media family planning campaign on contraception related behavior. The study takes place in Burkina Faso, a country with an average of six children born to each woman, and a modern contraceptive prevalence rate (mCPR) estimated at 15% in 2010 at the national level, as per the Demographic Health Survey (DHS) 2010 report on Burkina Faso. The aim of this study is to provide robust evidence on the efficiency and cost-effectiveness of an intense three-year mass media campaign focused on family planning. The campaign will diffuse messages about the financial and health benefits of family planning, and information on the different types, sources, advantages, and disadvantages of different contraceptive methods. The study will target women at the age of reproduction in rural areas of Burkina Faso to measure the effect of the intervention on total and modern contraceptive prevalence rates, perceptions of family planning, contraception-related behavior, and general gender norms. Burkina Faso is an ideal place to evaluate the impact of a radio campaign because a high percentage of the rural population listens to local radio which is in the local language. Radio station areas are distinct because they target very local languages and their reach is limited by government decree, which allows for the implementation of a randomized control trial.

NCT ID: NCT02585999 Active, not recruiting - Contraception Clinical Trials

PK Patch 12 Week Continuous Use

Start date: October 2015
Phase: Phase 4
Study type: Interventional

Investigators propose a descriptive pharmacokinetic study of the serum hormone levels of estrogen and progesterone with extended use (12 weeks) of the contraceptive patch. The primary objective is to assess the change in serum Ethinyl Estradiol (EE2) levels over 12 weeks of continuous contraceptive patch use. Additional objectives include assessing the EE2 area under the curve (AUC) during the study time period, as well as Norelgestromin (NGMN) levels and NGMN AUC over the 12 weeks of continuous contraceptive patch use.

NCT ID: NCT02146950 Active, not recruiting - Contraception Clinical Trials

European Active Surveillance Study of LCS12

EURAS_LCS12
Start date: June 17, 2014
Phase:
Study type: Observational

This study is designed to investigate whether LCS12 is associated with an increased risk of unintended pregnancy compared to Mirena and to copper IUDs. The objective is to assess among new users the risks of certain events (e.g. contraceptive failure rate, ectopic pregnancy, uterine perforation, and PID) associated with the use of LCS12 compared with the established hormonal IUD Mirena, and compared with established copper IUDs during standard clinical practice. In addition, drug utilization patterns will be described.

NCT ID: NCT02076217 Active, not recruiting - Contraception Clinical Trials

Quick Start of Highly Effective Contraception

Start date: February 2014
Phase:
Study type: Observational

This project will quantify rates of contraceptive failure when unprotected intercourse occurs 6-14 days prior to initiation of highly effective reversible contraceptives (such as IUD's and Implants).

NCT ID: NCT01986439 Active, not recruiting - Contraception Clinical Trials

The Contraceptive Choice Project

Start date: August 2007
Phase: N/A
Study type: Observational

The purpose of this project is to remove barriers to obtaining contraceptive methods, including the most effective and expensive methods. The study seeks to remove the financial and knowledge barriers and promote the most effective contraceptive methods to reduce unintended pregnancy rates at the population level.