Clinical Trials Logo
  1. Home
  2. Congenital Disorders
  3. NCT00268112

Resynchronization of Left Ventricular Contraction After Reimplantation of Anomalous Left Coronary Artery

Congenital Disorders Clinical Trial

Official title:
Resynchronization of Left Ventricular Contraction After Re-implantation of Anomalous Left Coronary Artery From the Pulmonary Artery (ALCAPA) Evaluated by Tissue Doppler Imaging

Clinical Trial Summary

Spontaneous resynchronization of dyskinetic segments of the left ventricle occurs after coronary bypass surgery in adults and has been shown in some children. It is, however, unknown what degree of dyskinesis is likely to be reversible in infants with ischemia from anomalous coronary arteries and what criteria would indicate that a resynchronization strategy of biventricular pacing might be needed.

These questions need data from quantitative serial tissue Doppler observations of patients from pre-operative to late post-operative follow-up.

Clinical Trial Description

We have previously studied, at Children's Healthcare of Atlanta, Egleston Hospital, 2 patients with ALCAPA and one other patient is currently enrolled in a prospective study after recent surgery, also at Children's Healthcare of Atlanta. We propose to study these 3 patients with this rare defect concurrently with their routine echocardiographic evaluations. Data will then be taken off-line for analysis.

Standard deviations of times to peak contraction velocity will be assessed for twelve cardiac segments. These will be reevaluated at follow up intervals after surgery on previously obtained echocardiograms. Those subjects in whom improvement of cardiac function, Left Ventricular Ejection Fraction (LVEF) and mitral regurgitation is seen will be compared to those in whom no improvement occurs. ;

Study Design

Time Perspective: Retrospective

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT00268112
Study type Observational
Source Children's Healthcare of Atlanta
Contact
Status Terminated
Phase N/A
Start date January 2004
Completion date December 2006
View Details
See also
  Status Clinical Trial Phase
Recruiting NCT04405700 - Measuring Adverse Pregnancy and Newborn Congenital Outcomes
Not yet recruiting NCT03291678 - Impact of Percutaneous Laparoscopic Assisted Internal Ring Ligation During Lap Orchiopexy N/A
Completed NCT00489788 - Predictors for Pulmonary Valve Replacement - Anatomic and Hemodynamic Using MRI N/A
Terminated NCT00268060 - Infant Medical Records: Case Report Proposal N/A
Not yet recruiting NCT05955794 - Vocal Pattern Assessment as a New Key to Identifying Rare Syndromes N/A
Completed NCT00257517 - Multisite Feeding Study: Home Surveillance and Feeding Strategies in Infants With Complex Single Ventricle N/A
Completed NCT00478296 - Pulmonary Hypertension in Trisomy 21 Patients N/A
Completed NCT04556487 - Turkish Affordances in the Home Environment for Motor Development-Infant Scale (AHEMD-IS)
Terminated NCT00261989 - Pulse Oximetry Readings and Hourly Variation in Oximetry Readings With CHD N/A
Completed NCT00211081 - Spironolactone in Patients With Single Ventricle Heart N/A
Terminated NCT00268099 - Optimal Timing for Repair of Right-to-Left Shunt Lesions N/A
Active, not recruiting NCT05752019 - TAAI Erasmus Research Initiative to Fight CF: Monitoring Inflammation in CF Lung Disease Into a New Era
Completed NCT00490295 - Biomarkers for Detection of Brain Ischemia N/A
Terminated NCT00327899 - Home Inotropic Therapy in Children N/A
Terminated NCT00229905 - Child With Anomalous Drainage of IVC to Left Atrium N/A
Completed NCT00277901 - MRI Assessment of RV Function: Patients With TOF or Aortic Coarctation N/A
Terminated NCT00366314 - Frequency of Accessing Central Lines for Blood Samples N/A
Terminated NCT00268034 - Left Ventricular Aneurysms in Children N/A
Completed NCT00366847 - Computer Modeling of Congenital Heart Disease N/A
Withdrawn NCT00460824 - A Retrospective Review - Anti-HLA Antibodies N/A