Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration

Congenital Diaphragmatic Hernia Clinical Trial

Official title:

Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT05985564
• Other study ID #: ysong
• Status: Recruiting
• Start date: March 18, 2022
• Est. completion date: December 31, 2023

Study information

• Verified date: August 2023
• Source: Children's Hospital of Chongqing Medical University
• Contact: song yan
• Phone: 13637921652
• Email: doctorsongyan[@]163.com
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The imaging manifestations of diaphragmatic hernia and diaphragmatic distension were retrospectively analyzed and summarized, combined with the surgical findings, to summarize the differences in indirect signs of diaphragmatic hernia and diaphragmatic distension, so as to achieve the purpose of differential diagnosis.Research contents: (1) To summarize the characteristics of indirect imaging signs in patients with diaphragmatic hernia, to sum up the incidence of each sign, to find new signs and the prognosis of each sign; (2) Summarize the characteristics of indirect imaging signs in patients with diaphragmatic distension, summarize the incidence of each sign, and search for new signs and the prognosis of each sign; (3) To summarize the differences in indirect signs of diaphragmatic hernia and diaphragmatic distension, as well as the differences in their incidence, and combined with their surgical findings, to summarize their image identification points

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 300
• Est. completion date: December 31, 2023
• Est. primary completion date: October 31, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A to 14 Years

Eligibility

Inclusion Criteria:

• Clinical diagnosis of diaphragmatic hernia with surgical treatment

• Clinical diagnosis of congenital diaphragmatic eventration with surgical treatment

Exclusion Criteria:

• Diaphragmatic hernia or congenital diaphragmatic eventration without surgical treatment

• Diaphragmatic hernia or congenital diaphragmatic eventration without imaging examination

Related Conditions & MeSH terms

• Congenital Diaphragmatic Hernia
• Diaphragmatic Eventration
• Hernia
• Hernia, Diaphragmatic
• Hernias, Diaphragmatic, Congenital

Intervention

Other:
• imaging diagnosis
no intervention

Locations

Country	Name	City	State
China	Children's Hospital of Chongqing Medical University	Chongqing

Sponsors (1)

Lead Sponsor	Collaborator
Children's Hospital of Chongqing Medical University

Country where clinical trial is conducted

China, 

References & Publications (3)

Alamo L, Gudinchet F, Meuli R. Imaging findings in fetal diaphragmatic abnormalities. Pediatr Radiol. 2015 Dec;45(13):1887-900. doi: 10.1007/s00247-015-3418-5. Epub 2015 Aug 9. — View Citation

Brown BP, Clark MT, Wise RL, Timsina LR, Reher TA, Vandewalle RJ, Brown JJ, Saenz ZM, Gray BW. A multifactorial severity score for left congenital diaphragmatic hernia in a high-risk population using fetal magnetic resonance imaging. Pediatr Radiol. 2019 Dec;49(13):1718-1725. doi: 10.1007/s00247-019-04478-2. Epub 2019 Aug 14. — View Citation

Goodfellow T, Hyde I, Burge DM, Freeman NV. Congenital diaphragmatic hernia: the prognostic significance of the site of the stomach. Br J Radiol. 1987 Oct;60(718):993-5. doi: 10.1259/0007-1285-60-718-993. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The position of the stomach	The position of the stomach through imaging examination and operation	1 day during the test
Primary	The position of the small intestine	The position of the small intestine through imaging examination and operation	1 day during the test
Secondary	The morphology of the small intestine	The normal morphology, dilation and stenosis of the small intestine through imaging examination	1 day during the test
Secondary	The position of the colon	The position of the colon through imaging examination and operation	1 day during the test
Secondary	The morphology of the colon	The normal morphology, dilation and stenosis of the colon through imaging examination	1 day during the test