Community Infections Clinical Trial
Official title:
A Cohort Study to Assess the Impact of Paediatric Use of Proton Pump Inhibitors on the Risk of Community Acquired Infections
Pharmacological treatment of physiologic Gastro-esophageal Reflux disease (GERD) is
excessive in France, as 65%-85% of children below 11 years are being treated, frequently
with Proton Pump Inhibitors (PPIs) PPI have been associated, in adults, with an increase of
infection rate but data in pediatry are scarce, especially in community medecine. Recently a
study conducted in England brought up controversial results suggesting that the use of PPIs
can be associated with a reduced risk of community acquired pneumonia.
Our study was aimed to assess, on a population-based database, the association between PPI
prescription and community infections in children of 11 years or under.
n/a