Corticosteroid Therapy for Severe Community-Acquired Pneumonia

Status Recruiting

Clinical Trial Summary

The purpose of the present study is to assess the efficacy of methylprednisolone as an adjuvant therapy in patients with severe community-acquired pneumonia (CAP) (PSI 4-5).

The hypothesis of the study is that methylprednisolone can decrease the mortality of severe CAP without any significant side effects,with reduction of the time to clinical stability and failure rate of treatment.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator, Outcomes Assessor), Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT02552342
Study type	Interventional
Source	Peking Union Medical College Hospital
Contact	Jun XU, MD
Phone	01069159142
Email	xujunfree@126.com
Status	Recruiting
Phase	Phase 4
Start date	May 2015
Completion date	May 2017

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT02559310` - Study to Compare Lefamulin to Moxifloxacin (With or Without Linezolid) for the Treatment of Adults With Pneumonia	Phase 3
Completed	`NCT01530763` - Safety and Efficacy Study of Ceftaroline Versus a Comparator in Pediatric Subjects With Community Acquired Bacterial Pneumonia (CABP)	Phase 2/Phase 3
Completed	`NCT02517489` - Community-Acquired Pneumonia : Evaluation of Corticosteroids	Phase 3
Completed	`NCT02454114` - HOME FIRST Pilot: a Study of Early Supported Discharge in Patients With Lower Respiratory Tract Infections	N/A
Not yet recruiting	`NCT01937832` - A Phase III Study of Faropenem in the Treatment of Adult Community-acquired Bacterial Pneumonia	Phase 3
Completed	`NCT00653172` - Comparative Study of NXL103 Versus Comparator in Adults With Community Acquired Pneumonia	Phase 2
Recruiting	`NCT02139163` - Epidemiological Study on Community Acquired Pneumonia
Completed	`NCT03411824` - Lung Ultrasound for Community-acquired Pneumonia Diagnosis in Emergency Medicine
Recruiting	`NCT06210282` - The Effect of Focused Lung Ultrasonography on Antibiotic Prescribing in General Practice	N/A
Withdrawn	`NCT02269644` - A P3 Comparator Trial in Community Acquired Bacterial Pneumonia	Phase 3
Recruiting	`NCT01963442` - Short Duration Treatment of Non-severe Community Acquired Pneumonia	Phase 2
Terminated	`NCT00887276` - Study to Proof the Clinical and Bacteriological Non-inferiority of Ampicillin/Amoxicillin Versus Moxifloxacin in Hospitalized Patients With Non-severe Community-acquired Pneumonia	Phase 4
Not yet recruiting	`NCT00390819` - Epidemiology of Community Acquired Pneumonia in North Israel	N/A
Completed	`NCT00079885` - Study Evaluating Tigecycline vs Levofloxacin in Hospitalized With Community-Acquired Pneumonia	Phase 3
Not yet recruiting	`NCT04158310` - Evaluation the Clinical Value of Xiyanping Injection in the Treatment of Community-acquired Pneumonia in Children
Completed	`NCT02922387` - Smoking Cessation Intervention in Respiratory Inpatients	Phase 4
Completed	`NCT00467701` - Community Acquired Pneumonia in Telemark and Ostfold	N/A
Completed	`NCT04198571` - Retrospective Chart Review Study to Assess Characteristics, Treatment Outcomes and Resource Use of Adults Hospitalized for CAP and CSSTi Treated With Zinforo in Multiple Countries
Completed	`NCT02107001` - Lung Ultrasound in Pleuritic Chest Pain	N/A
Completed	`NCT01561885` - Collaborative Healthcare Professionals Approach in Monitoring of Patient Centered Outcomes Through Pathways	N/A