Impact of Screen Size on Colorectal Adenoma Detection

Status Recruiting

Clinical Trial Summary

The purpose of this study is to assess whether the use of large screen during colonoscopy will increase adenoma detection rate.

Clinical Trial Description

Colorectal cancer is the 3rd most common cancer in the world. Recently in Hong Kong it has surpassed lung cancer to be the most common cancer. Hence it is essential not only to have up-to-date surgical and oncological treatment but also a need an effective preventative strategy. In the past few decades, removal of pre-malignant colonic lesions such as adenomas have been shown to prevent development of colorectal cancers. Colonoscopy is currently the only technique which can perform both detection and treatment during the same procedure. However, concerns have been raised about the effectiveness of colonoscopy in the prevention of CRC after several studies reported unexpected high incidence rates of interval carcinomas (IC), especially in the proximal colon. Most ICs are suspected to arise from missed colon lesions during colonoscopy. Factors concerning missed colonic lesions are multifactorial such as adequate bowel preparation, skill level of endoscopists, the number of endoscopy staff in the room as "eyes" to help with polyp detection and withdrawal time. Following a pilot study in our endoscopy unit, we believe the size of the screen projecting the endoscopic image may have a positive influence on adenoma detection. Therefore, we feel that a well-designed and adequately powered randomised controlled trial may help to confirm this. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04749303
Study type	Interventional
Source	Chinese University of Hong Kong
Contact
Status	Recruiting
Phase	N/A
Start date	July 1, 2020
Completion date	August 31, 2021

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04552093` - Hepatic Arterial Infusion Pump Chemotherapy Combined With Systemic Chemotherapy (PUMP-IT)	Phase 2/Phase 3
Completed	`NCT04192565` - A Prospective Investigation of the ColubrisMX ELS System	N/A
Completed	`NCT05178745` - A Prospective Observational Cohort Study Evaluating Resection Rate in Patients With Metastatic Colorectal Cancer Treated With Aflibercept in Combination With FOLFIRI - Observatoire résection
Recruiting	`NCT03561350` - Detect Microsatellite Instability Status in Blood Sample of Advanced Colorectal Cancer Patients by Next-Generation Sequencing
Recruiting	`NCT06128798` - Effect of Preoperative Immunonutrition Versus Standard Oral Nutrition in Patient Undergoing Colorectal Surgery.	N/A
Recruiting	`NCT03602677` - Indocyanine Green Fluorescence Imaging in Prevention of Colorectal Anastomotic Leakage	N/A
Completed	`NCT03631407` - Safety and Efficacy of Vicriviroc (MK-7690) in Combination With Pembrolizumab (MK-3475) in Participants With Advanced/Metastatic Microsatellite Stable (MSS) Colorectal Cancer (CRC) (MK-7690-046)	Phase 2
Withdrawn	`NCT04192929` - Chromoendoscopy or Narrow Band Imaging (NBI) for Improving Adenoma Detection in Colonoscopy	N/A
Recruiting	`NCT03042091` - Neomycin and Metronidazole Hydrochloride With or Without Polyethylene Glycol in Reducing Infection in Patients Undergoing Elective Colorectal Surgery	Early Phase 1
Completed	`NCT02889679` - Underwater Resection of Non-pedunculated Colorectal Lesions	N/A
Terminated	`NCT02842580` - De-escalation Chemotherapies Versus Escalation in Non Pre-treated Unresectable Patients With Metastatic Colorectal Cancer	Phase 2
Completed	`NCT02564835` - Effects of Yoga on Cognitive and Immune Function in Colorectal Cancer	N/A
Completed	`NCT02149108` - Nintedanib (BIBF 1120) vs Placebo in Refractory Metastatic Colorectal Cancer (LUME-Colon 1)	Phase 3
Completed	`NCT02503696` - Sample Collection Study to Evaluate DNA Markers in Subjects With Inflammatory Bowel Disease (IBD)	N/A
Completed	`NCT02599103` - The Effects of Various Cooking Oils on Health Related Biomarkers in Healthy Subjects	N/A
Completed	`NCT01719926` - Phase I Platinum Based Chemotherapy Plus Indomethacin	Phase 1
Completed	`NCT01669109` - Hatha Yoga for Patients With Colorectal Cancer	N/A
Recruiting	`NCT01428752` - Study of Prevalence of Colorectal Adenoma in 30- to 49-year-old Subjects With a Family History of Colorectal Cancer	N/A
Completed	`NCT01978717` - General Anesthesia Combined With Epidural Anesthesia Mitigates the Surgical Stress-related Immunosuppression in Patients With Colorectal Cancer	N/A
Completed	`NCT01877018` - Colorectal Cancer Screening in Primary Care	N/A