PACE: PD-1 Antibody For dMMR/MSI-H Stage III Colorectal Cancer

Status Recruiting

Clinical Trial Summary

In this open-label phase III study, patients with local advanced colon cancer (TanyN+ ,M0, dMMR/MSI-H, at least 10cm from the anus verge)will be scheduled to Group A: receive anti-PD-1 antibody alone (8 cycles, 200mg iv drip Q3W) and Group B (4 or 8 cycles of XELOX: oxaliplatin 130mg/m2 day 1, capecitabine 2000mg/m2 days 1-14, repeated every 21 days). The primary endpoint was 3 Disease-free survival; analyses were done based on all patients with post-randomization data.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05236972
Study type	Interventional
Source	Sun Yat-sen University
Contact	Peirong Ding, professor
Phone	+86-13543478645
Email	dingpr@sysucc.org.cn
Status	Recruiting
Phase	Phase 3
Start date	January 1, 2022
Completion date	December 31, 2028

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