Colorectal Cancer Clinical Trial
Official title:
Prognostic Value of EGFR Expression, KRAS Mutation and Tumor Sideness in Patients With Metastatic Colorectal Cancer Treated With Regorafenib and FOLFIRI as a Third- or Fourth-line Setting
The survey is a retrospective study to evaluate the prognotic value of EGFR expression, KRAS mutations and tumor sideness in patients with metastatic colorectal cancer treated with regorafenib and FOLFIRI as a third- or fourth-line setting.
Primary objective:
Progression-free survival
Secondary objecive:
Overall survival, best objective response, disease control rate and adverse events
Number of Subjects: 41 patients with metastatic colorectal cancer treated with regorafenib
and FOLFIRI as a third- or fourth-line setting.
Plan of the Study:
1. This is a retrospective study.
2. Study Schedule Study date: the time getting approval letter issued by both regulatory
authority and institutional review board (IRB). Duration of the study: 5 years.
3. Duration of Treatment: Treatment was administered until disease progressed.
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