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Clinical Trial Summary

4L split dose PEG is the gold standard for bowel preparation, however it comes with poor tolerability and poor compliance. Combination of PEG with different agent is useful in reducing total volume, improving compliance and tolerance of patient. The objective of this study is to demonstrate that combination bowel preparation, PEG plus SPMC solution, has similar efficacy and safety profile whereas with a better tolerance when compared to large volume PEG.


Clinical Trial Description

This is a prospective, randomized, single-center, single-blinded, non-inferiority trial. Participants with out patient colonoscopy arranged will be included and randomized in a 1:1 ratio to receive either a split dose of 4L PEG + Electrolyte (Klean-prep® ) or 1L Klean-prep® plus 2 sachets SPMC (Picoprep®). Trained endoscopists will be using the Boston Bowel Preparation Scale (BBPS) to assess the quality of bowel preparation. Patient would also rate the tolerance, compliance and adverse effect by filling the questionnaire before the colonoscopy. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04474002
Study type Interventional
Source Queen Elizabeth Hospital, Hong Kong
Contact Yau Kan Tso
Phone 00852 35067479
Email tyk895@ha.org.hk
Status Recruiting
Phase Phase 4
Start date December 7, 2020
Completion date December 2022

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