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Clinical Trial Summary

The primary objective of this study is to determine if cryotherapy is beneficial to patients with colon cancer who are receiving oxaliplatin in the prevention of developing chemotherapy induced peripheral neuropathy.


Clinical Trial Description

Peripheral neuropathy often manifests as numbness and tingling in the hands and feet, which may be detrimental to the patients' overall safety and quality of life, thereby causing them to stop or delay treatment. Everyday tasks such as walking, buttoning a shirt, or tying shoes can become challenging. Select chemotherapy agents are known to cause significant peripheral neuropathy. Studies have been performed demonstrating efficacy of using cryotherapy, which causes vasoconstriction, to targeted areas of the body, in relation to paclitaxel. These studies have shown drastic differences between those who receive cryotherapy during treatment and those who do not. There are few studies on the use of cryotherapy in the prevention of peripheral neuropathy with the use of oxaliplatin, which will be undertaken in this study. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06281925
Study type Interventional
Source NYU Langone Health
Contact Sarah Mendez
Phone 347-835-7771
Email Sarah.mendez@nyulangone.org
Status Not yet recruiting
Phase N/A
Start date April 2024
Completion date December 31, 2025

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