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Colitis clinical trials

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NCT ID: NCT00209287 Terminated - Ulcerative Colitis Clinical Trials

Study of Effects and of Modifications in Apoptosis Regulators Observed After Stopping 5-ASA Treatment in Patients With Inactive Ulcerative Colitis

Start date: June 2005
Phase: Phase 4
Study type: Interventional

Male or female, 18 years of age or older. Ulcerative Colitis described according usual criteria, diagnosed for at least 1 year. Oral maintenance treatment with 5-aminosalicylic acid (5-ASA) only for at least 3 months with a dosage of 2 to 3 g/day. Clinical remission for at least 3 months (Mayo Clinic score) and endoscopic remission (endoscopic score of Mayo Clinic) at the inclusion. Signed informed consent form.

NCT ID: NCT00207688 Completed - Ulcerative Colitis Clinical Trials

A Long Term Safety Study of Infliximab (Remicade) in in Ulcerative Colitis Patients

Start date: August 31, 2004
Phase:
Study type: Observational

The purpose of this study is to evaluate long-term safety information of infliximab in patients who have participated in infliximab clinical studies in ulcerative colitis.

NCT ID: NCT00194818 Completed - Ulcerative Colitis Clinical Trials

Asacol Dosing Study for Active Ulcerative Colitis

Start date: June 2003
Phase: Phase 4
Study type: Interventional

We, the investigators at University of Washington, plan on evaluating the effect of open label Asacol at a dose of 4.8 grams/day divided BID (twice per day) or TID (three times per day) on its ability to induce remission in patients with mild to moderately active ulcerative colitis. We hypothesize that both regimens will have the same efficacy and no difference in side effects.

NCT ID: NCT00184171 Terminated - Colitis Clinical Trials

Treatment of Microscopic Colitis

Start date: November 2001
Phase: N/A
Study type: Interventional

The study compares the effect of Budesonide, Bismuth and fiber in patients with microscopic colitis

NCT ID: NCT00180076 Completed - Collagenous Colitis Clinical Trials

Budesonide for Maintenance Treatment of Collagenous Colitis

Start date: July 2004
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether orale budesonide is effective in maintaining clinical remission in patients with collagenous colitis.

NCT ID: NCT00180050 Completed - Microscopic Colitis Clinical Trials

Budesonide Treatment for Lymphocytic Colitis

Start date: January 2002
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether orale budesonide is effective in the treatment of lymphocytic colitis

NCT ID: NCT00152841 Terminated - Ulcerative Colitis Clinical Trials

Effect of Iron and Vitamin E Supplementation on Disease Activity in Patients With Either Crohn's Disease or Ulcerative Colitis

Start date: June 2002
Phase: Phase 2
Study type: Interventional

Hypothesis:In patients with ulcerative colitis and Crohn's disease diagnosed with mild or moderate anaemia: 1. iron supplementation will increase disease activity and oxidative stress 2. the addition of antioxidant vitamin will reduce this detrimental effect

NCT ID: NCT00151944 Completed - Colitis, Ulcerative Clinical Trials

Safety and Tolerability of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis.

Start date: November 26, 2003
Phase: Phase 3
Study type: Interventional

The purpose of this study is to test the long-term safety and tolerability of SPD476 in the maintenance of ulcerative colitis remission.

NCT ID: NCT00151892 Completed - Ulcerative Colitis Clinical Trials

Efficacy and Safety of SPD476 in Maintaining Remission in Patients With Ulcerative Colitis

Start date: April 8, 2005
Phase: Phase 3
Study type: Interventional

Ulcerative colitis is a disease of the large bowel (colon) and rectum in which the lining of the bowel becomes red and swollen. Over time, patients with this disease may experience acute episodes of diarrhea, rectal bleeding and abdominal pain followed by periods of time without disease symptoms. 5-ASA drugs are a standard treatment for ulcerative colitis. Mesalazine is an experimental drug designed to gradually release 5-ASA into the areas of large bowel associated with ulcerative colitis. This study will test the safety and efficacy of mesalazine in keeping ulcerative colitis in remission.

NCT ID: NCT00145808 Completed - Ulcerative Colitis Clinical Trials

Wireless Capsule Endoscopy in Ulcerative Colitis

Start date: June 2005
Phase: Phase 3
Study type: Interventional

Based on the inaccuracies of the current classification scheme for inflammatory bowel disease (IBD), the failure of surgical pouches and the findings of retrospective observational trials to date, we hypothesize that a significant proportion of patients with UC will have small bowel involvement that will result in a change in diagnosis to CD or the recognition of a new phenotype of IBD. The aim of this study is to determine the prevalence of small bowel pathology in patients diagnosed with UC using WCE. This information will aid in the current efforts to re-classify IBD using improved endoscopic and imaging technologies, genetic information and serologic information.