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Colitis, Ulcerative clinical trials

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NCT ID: NCT01320332 Completed - Ulcerative Colitis Clinical Trials

A Study of a Single Dose of ASP3291 in Subjects With Ulcerative Colitis

Start date: August 2010
Phase: Phase 1
Study type: Interventional

The purpose of this study is to determine the pharmacokinetics (PK) and to assess safety and tolerability of a single dose of ASP3291 in subjects with ulcerative colitis.

NCT ID: NCT01301976 Completed - Clinical trials for Ulcerative Colitis in Remission

Nutritional State and Intake Nutrients Assessment in Ulcerative Colitis

Start date: March 2009
Phase: N/A
Study type: Observational

The purpose of this study is to determine the reason patients are deficient in nutrients intake such as antioxidants vitamins.

NCT ID: NCT01301417 Completed - Lymphoma Clinical Trials

Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis

RETROPRESS
Start date: February 2011
Phase: N/A
Study type: Observational

The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing™ device in routine clinical practice at a single center. The data will assist in further evaluating the performance of the ColonRing™ device in regards to the creation of a colorectal anastomosis. Hypothesis:The performance of the ColonRing™, determined by the rate of complications, will be within the acceptable range reported in the literature for alternative treatment modalities.

NCT ID: NCT01296841 Completed - Ulcerative Colitis Clinical Trials

Telemedicine To Provide Inflammatory Bowel Disease Outpatient Care

Start date: October 2009
Phase: Phase 2
Study type: Interventional

The investigators hypothesize that outpatient clinical care of Inflammatory Bowel Disease patients may be provided using a new computerized system over standard network - called Collaborative Imaging - with similar patient experience compared to a conventional clinic visit.

NCT ID: NCT01294410 Completed - Colitis, Ulcerative Clinical Trials

Induction and Maintenance Study of BMS-936557 Patients With Moderate to Severe Ulcerative Colitis

Start date: March 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether BMS-936557 is effective in the treatment of moderate to severely active ulcerative colitis in patients who have had insufficient response and/or intolerance to other medical therapy for ulcerative colitis

NCT ID: NCT01293656 Withdrawn - Ulcerative Colitis Clinical Trials

Study of Participants With Crohn's Disease and Ulcerative Colitis in Eastern Europe, Middle East, and North Africa (P08166)

Start date: August 2011
Phase: N/A
Study type: Observational

This study is being done to assess the clinical course and treatment options for Crohn's Disease (CD) and ulcerative colitis (UC) in the populations of Eastern Europe, Middle East, and North Africa.

NCT ID: NCT01290042 Completed - Ulcerative Colitis Clinical Trials

Study to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AMG 181.

Start date: February 2011
Phase: Phase 1
Study type: Interventional

To assess the safety and tolerability of multiple subcutaneous doses of AMG 181 in healthy subjects, in subjects with active ulcerative colitis, and in subjects with active Crohn's disease.

NCT ID: NCT01289366 Completed - Ulcerative Colitis Clinical Trials

Endocytoscopy for in Vivo Determination of Mucosal Inflammatory Cells and Intestinal Disease Activity in Inflammatory Bowel Disease (IBD)

Start date: May 2010
Phase: N/A
Study type: Observational

Precise activity assessment of inflammatory bowel disease (IBD) is essential to determine the extent and severity of the disease for further specific therapy. Nevertheless, despite ongoing developments in the field of gastrointestinal endoscopy, the final diagnosis still relies on the interpretation of histopathological features of intestinal biopsies taken during the endoscopic examination. Recently, endocytoscopy (EC) was introduced as a new endoscopic imaging modality, enabling microscopic imaging within the mucosal layer of the gut at a magnification level of up to 1400-fold.

NCT ID: NCT01287195 Completed - Ulcerative Colitis Clinical Trials

Oral OKT3 for the Treatment of Active Ulcerative Colitis

Start date: April 7, 2011
Phase: Phase 1/Phase 2
Study type: Interventional

This study will assess the safety and efficacy of orally delivered short-term OKT3 in participants with active ulcerative colitis.

NCT ID: NCT01284062 Completed - Colitis, Ulcerative Clinical Trials

Pharmacokinetics/Pharmacodynamics Biomarker Study in Active Ulcerative Colitis Patients

Start date: March 2011
Phase: Phase 2
Study type: Interventional

This study represents the first investigation of anrukinzumab in patients with active ulcerative colitis (UC) and will evaluate proof of mechanism by changes in the mechanism based biomarker (YKL 40) and pharmacodynamic biomarkers (fecal calprotectin, lactoferrin and hs-CRP). It will provide further assessment of the safety, tolerability, and pharmacokinetics (PK) by administration of multiple intravenous (IV) doses of anrukinzumab.