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Cold Exposure clinical trials

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NCT ID: NCT06159374 Recruiting - Hypoxia, Altitude Clinical Trials

Effects of Physical Training in Altered Environmental Conditions on Exercise Performance

Start date: January 1, 2022
Phase: N/A
Study type: Interventional

The main objective of the study is to evaluate the physiological-biochemical effects of physical training under artificially altered climatic conditions (using a hypoxic thermoclimatic chamber) in particular to determine the effect of such training on exercise capacity and physiological response, including the effect of training in high-performance athletes. The study will evaluate the effects of physical training and the simultaneous application of hypoxia and heat/cold on aerobic and anaerobic capacity and the physiological response of the human body. The aim of the study is to find the most favourable environmental conditions for physical training in order to maximise physical performance.

NCT ID: NCT05822141 Recruiting - Cold Exposure Clinical Trials

Omega-3 Fatty Acids as Regulators of Brown Adipose Tissue During Cold Exposure

Start date: June 12, 2023
Phase: N/A
Study type: Interventional

This clinical trial will assess the whether fish oil supplementation can modulate brown fat activation, shivering, thermal comfort and skin blood flow during cold exposure.

NCT ID: NCT05584527 Recruiting - Eating Habit Clinical Trials

Assessment of the Effects of a 24-hour Cold and Heat Exposure on the Factors Influencing Food Intake

TEMPCA
Start date: November 28, 2022
Phase:
Study type: Observational

Military personnel and athletes have a very high energy expenditure which is increased during certain key periods (intense training, competition and mission). Compensating for this expenditure through food can be complicated by physiological ingestive limits and logistical and organizational constraints (number of meals, availability of food), which leads these populations to regularly experience energy deficit situations (intake below requirements), which could alter physical and cognitive performance and major physiological functions. Among the many constraints to which military personnel and athletes are exposed to (stress, sleep deprivation, travel, etc.) that can increase the risk of energy deficits, the impact of thermal environmental constraints is not well known. The seasonal impact and travel to countries with very different thermal environments can lead these populations to experience cold and hot conditions for long periods. Understanding how heat and cold exposure modifies appetite and energy intake therefore appears to be of great importance. The hypothesis of this study is that a 24 h heat exposure would produce a rapid and long-lasting anorexigenic action impacting energy intake, while a cold exposure would produce the opposite effect (orexigenic action).

NCT ID: NCT05464758 Recruiting - Cold Exposure Clinical Trials

The Effects of Cold Adaptation on Skin Blood Flow, Hand Function, and Comfort in Healthy Adults

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

In cold weather environments, blood flow to the extremities is significantly reduced, which severely impairs hand function and induces thermal discomfort. Prolonged or repeated cold exposure elicits an adaptive habituation response that is characterized by blunted skin vasoconstriction and thus may be an effective strategy to improve peripheral perfusion, reduce thermal discomfort, and maintain hand function during cold weather military operations. Since mission conditions often involve low ambient temperatures, countermeasures that reduce cold-induced decrements in hand function and thermal comfort are important to enhance Warfighter readiness in cold weather battlefield environments. The goals of this study are to 1) evaluate the effectiveness of cold habituation in improving skin blood flow, hand function, and thermal comfort during cold exposure and 2) identify the mechanisms that contribute to improvements in skin blood flow following habituation.

NCT ID: NCT05076357 Recruiting - Weight Loss Clinical Trials

Cold, Appetite and Weight Loss in Individuals With Obesity

Start date: February 1, 2022
Phase: N/A
Study type: Interventional

This study is an 8 week weight loss intervention with 3 randomly assigned groups: DIET, cold exposure (CE), and DIET+CE. The study will be a total of 13 weeks. All participants will undergo a screening session, two experimental sessions at baseline and two experimental sessions after the intervention. There will be a control (ambient) experimental session and a cold exposure experimental session These will be done in a randomized order both before and after the intervention. Therefore, a total of 5 lab visits will be required for all participants regardless of group outside of their assigned group intervention. Participants in the CE and DIET+CE groups will report to the laboratory every 2nd day for the 8 week intervention to undergo cold exposure as outlined below. The DIET and DIET+CE groups will have a weekly nutritional consultation at the lab as well as a weekly check-in with the nutritionist via text, phone, or email. Participants will be randomly assigned a group after completing the screening session and prior to the experimental session.

NCT ID: NCT04359082 Recruiting - Gut Microbiome Clinical Trials

Cocoa-rich Bioflavanol Supplementation Effects During Cold Exposure

Start date: January 13, 2020
Phase: N/A
Study type: Interventional

The primary purpose is to test whether cocoa-rich bioflavanols can improve blood flow to the hand and fingers and improve hand function/dexterity during cold exposure. Secondary purpose is to understand whether bioflavanol supplementation can change the gut microbiome.