Compensatory and Restorative Rehabilitation Techniques in Stroke

Cognitive Impairment Clinical Trial

— The  

Official title:

Combined Effects of Restorative and Compensatory Rehabilitation Techniques on Executive Functions in Stroke With Mild Cognitive Impairment

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06325085
• Other study ID #: Ayesha Saddiqa
• Status: Recruiting
• Phase: N/A
• Start date: April 16, 2024
• Est. completion date: April 20, 2025

Study information

• Verified date: April 2024
• Source: Riphah International University
• Contact: Dr.Aroosa Tariq, MS-NMPT
• Phone: 03161578156
• Email: aroosa.tariq[@]riphah.edu.pk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The aim of this randomized controlled trial is to find the combined effects of restorative and compensatory cognitive rehabilitation techniques in mild cognitive impairment after stroke.

Description:

Stroke is a prevalent medical neurological condition that often results in cognitive impairments, particularly in the domain of executive functions. Cognitive impairment has a significant impact on executive function in stroke subjects. Cognitive impairment on the stroke survivor exist on any single domain such as attention, spatial ability, language and executive ability more frequently than the multiple domains. Cognitive training has been shown to be beneficial for rehabilitation of patients with cognitive impairment, but the underlying mechanisms remain unclear. The combination of restorative and compensatory rehabilitation techniques is beneficial for gaining control over cognitive rehabilitation techniques will improve executive functions. The retention effects evaluated additionally will add a broad insight in this regard. It will improve the learning power of brain through neural plasticity. This leads to restoration of everyday functioning. This study aims to investigate the effects of two distinct rehabilitation approaches on the executive functions of stroke survivors with MCI. Understanding how these rehabilitation strategies impact cognitive recovery is essential for individuals living with post-stroke cognitive impairments.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 36
• Est. completion date: April 20, 2025
• Est. primary completion date: March 20, 2025
• Accepts healthy volunteers: No
• Gender: All
• Age group: 50 Years to 70 Years

Eligibility

Inclusion Criteria:

• Age between 50 and 70 years
• Both Genders
• Individuals diagnosed with stroke 6 months before enrollment
• Minimum 6 years of schooling
• Patients with mild cognitive impairment (score 18-25 on MOCA)
• Individuals able to maintain sitting and standing balance (score 41 on berg balance scale)

Exclusion Criteria:

• >10 on post stroke depression rating scale (PSDRS)
• Spasticity (>3 on Ashworth scale)
• Other psychological disorders
• Patients diagnosed with Alzheimer's and dementia

Related Conditions & MeSH terms

• Cognitive Dysfunction
• Cognitive Impairment

Intervention

Other:
• compensatory and restorative rehabilitation techniques
compensatory and restorative rehabilitation techniques Frequency: 10 reps 2-3 times/week for 3 consecutive weeks then evaluation of the effects. Continue the same techniques for 3 more weeks and then evaluate the retention effects of restorative and compensatory rehabilitation techniques will be evaluated by 9th week.
• Traditional cognitive rehabilitation training
Naming words ( ask patient to name food, states, family members) Counting numbers backwards, backward counting of days and months) Spell the word backwards, remembering a piece of information Frequency: 10 reps 2-3 times/week for 3 consecutive weeks then evaluation of the effects. Continue the same techniques for 3 more weeks and then evaluate the retention effects of restorative and compensatory rehabilitation techniques will be evaluated by 9th week.

Locations

Country	Name	City	State
Pakistan	Shafi Hospital Dina	Dina	Punjab

Sponsors (1)

Lead Sponsor	Collaborator
Riphah International University

Country where clinical trial is conducted

Pakistan, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Montreal cognitive assessment test (Urdu version)	MOCA assesses different cognitive domains: attention and concentration, executive functions, memory, language, visuo-constructional skills, conceptual thinking and orientation. The test is one page,30 point test that can be administered in 10 minutes. MOCA is scored by obtaining an item total and the author recommend a clinical cutoff score of 26.is a Patient-completed, condition-specific functional status questionnaire with 10 items including pain, personal care, lifting, reading, headaches, concentration, work, driving, sleeping and recreation.	6 weeks
Primary	Cognitive assessment scale for stroke patients (CASP)	Its a rapid test for screening post stroke cognitive impairment. It can be performed at the patient bedside by a non expert examiner. A CASP score of 35/36 should alert to possible presence of cognitive impairment. Score can help predict medium level cognitive impairment.	6 weeks
Secondary	Stroke specific quality of life questionnaire (Urdu version)	The SS-QOL questionnaire assesses health related quality of life specific to stroke survivors covering almost 12 domains	6 weeks
Secondary	Modified Rankin Scale (MRS)	It measures degree of disability or dependence in daily activities of people who have suffered stroke or other neurological disability. It is one of the most widely used clinical patients are graded	6 weeks