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Cognitive Disorders clinical trials

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NCT ID: NCT05888961 Recruiting - Cognitive Disorders Clinical Trials

Single-center Prospective Longitudinal Study of Taste in Patients With Cognitive Disorders at Different Stages of Severity (Isolated Cognitive Complaint, Minor or Major Neurocognitive Alzheimer-type Disorders) by Analysis of Gustatory Evoked Potentials

MAPEG 2
Start date: June 12, 2023
Phase: N/A
Study type: Interventional

The aim of the MAPEG 2 study is to explore gustatory function and to follow its evolution in the 5 following groups of participants: - Healthy subjects - Participants with isolated cognitive complaint - Participants with minor neurocognitive disorder - Participants with mild Alzheimer-type major neurocognitive disorders - Participants with moderate Alzheimer-type major neurocognitive disorders For this purpose, we want to compare the results of the following tests: - Subjective taste tests (tasting solutions, answering food preference questionnaires), - Gustatory evoked potential (GEP) parameters, recorded by electrodes placed on the scalp, - And nutritional parameters (hormones of food intake by blood test, measurement of the global body composition). Identifying and following the evolution of early taste disorders in case of cognitive disorders could improve the diagnosis of Alzheimer's disease in two ways: - To allow an early diagnosis of Alzheimer's disease, and thus improve its management, - To define groups of subjects at risk of developing Alzheimer's disease in later years.

NCT ID: NCT04169633 Recruiting - Nursing Caries Clinical Trials

Spanish Adaptation and Validation of the Everyday Cognition Battery (ECB).

Start date: April 1, 2018
Phase:
Study type: Observational

HYPOTHESIS: The Spanish version of the Everyday Cognition Battery Scale (ECB) is valid and reliable in the Spanish population. OBJECTIVES: • Providing a validated scale in Spanish to evaluate daily cognition in older adults. SPECIFIC OBJECTIVES: - Translating the original English version of the ECB into Spanish. - Adapting the scale to the sociocultural context of Spain. - Checking the psychometric characteristics (reliability and validity) of the translated version . STUDY DESIGN: Cross-sectional descriptive study. Permission to use the ECB scale will be requested to the author, Allaire JC. Translation and adaptation of the scale. Administration of the four tests of the ECB to the individuals participating in the study. Administration of the Rapid Evaluation of Cognitive Functions (RECF) and Lawton and Brody scales. Analysis of the psychometric characteristics of the translated version. The protocol has been authorized by the Ethics Committee of the Salamanca health area to make the project possible.

NCT ID: NCT02876536 Recruiting - Multiple Sclerosis Clinical Trials

Effect of Transcutaneous Electrical Nerve Stimulation on Cognition in Multiple Sclerosis Patients

Start date: June 2016
Phase: N/A
Study type: Interventional

The aim of this study is to evaluate whether the Transcutaneous Electrical Nerve Stimulation (TENS) is effective on improvement of cognitive disorders in Multiple sclerosis patients.

NCT ID: NCT02782429 Recruiting - Dementia Clinical Trials

The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery

KeCoDy
Start date: April 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to analyze the Ketamine with its anti-inflammatory profile would be able to prevent cognitive disorders in the postoperative period of cardiac surgery, since these disorders contribute to an impact on morbidity / mortality in this population.

NCT ID: NCT02777060 Recruiting - Stroke Clinical Trials

Exploring the Effectiveness of Sensor-based Balance Training on Patient Outcome Measures

Start date: September 2014
Phase: N/A
Study type: Interventional

Explore the benefit of the game-based virtual reality system in improving lower extremity kinematics and balance in patients suffering from disease/disorders including Diabetes, Cancer, Multiple Sclerosis, Arthritis, Parkinson's disease, Cognitive Disorders, Brain Injury, Stroke or Frailty. A four to six weeks of training with 2 training session/week will be provided.

NCT ID: NCT01659593 Recruiting - Multiple Sclerosis Clinical Trials

Evaluation of the Efficiency of a Cognitive Remedial Program (PROCOG-SEP) Designed for Multiple Sclerosis Patients

PROCOG-SEP
Start date: September 2012
Phase: N/A
Study type: Interventional

Cognitive disorders are well-known in multiple sclerosis (MS), even in earlier stages of the disease. They effect personal life. Their management may be overlooked. The evidence-based program proposes exercises to both stimulate preserved functions and develop new abilities compensating for cognitive disabilities. Aim of the study is to evaluate the efficiency of the remedial program (PROCOG-SEP) designed for MS patients, compared to an interactive discussion program(DISINT) 140 multiple sclerosis patients will be randomly assigned in one the program for 13 sessions over a 6-month period. Main outcome criteria is evolution of SRT-LIST before and after program.

NCT ID: NCT01184638 Recruiting - Cognitive Disorders Clinical Trials

Long-term Outcome of General Anesthesia on Dysgnosia

LOGAND
Start date: August 2010
Phase: Phase 4
Study type: Interventional

Cognitive disorders in patients underwent general anesthesia are discussed for decades, but whether there were precise relationship between general anesthesia and dysgnosia is yet to be guaranteed. Although controversial data reported from experimental studies in animals, the investigators still proposed that general anesthetics could impair the normally organized system of the central nervous system, which finally displayed a dysfunction of cognition after general anesthesia in a short- or long-term period. Therefore, different types of general anesthetics such as inhalational anesthetics and intravenous anesthetics, the investigators hypothesized, had a long-term influence on patients' cognitive ability.