Clinical Trial Details
— Status: Active, not recruiting
Administrative data
NCT number |
NCT05290233 |
Other study ID # |
2022-0279 |
Secondary ID |
|
Status |
Active, not recruiting |
Phase |
N/A
|
First received |
|
Last updated |
|
Start date |
September 21, 2023 |
Est. completion date |
December 31, 2024 |
Study information
Verified date |
May 2024 |
Source |
University of Illinois at Chicago |
Contact |
n/a |
Is FDA regulated |
No |
Health authority |
|
Study type |
Interventional
|
Clinical Trial Summary
Time restricted eating (TRE) is currently the most popular form of intermittent fasting which
involves confining the eating window to 8-10 hours (h) and fasting for the remaining hours of
the day. TRE is unique in that during the eating window, individuals are not required to
count calories or monitor food intake in any way, resulting in high adherence. Accumulating
evidence suggests that TRE produces a natural energy deficit of ~350-500 kcal/d. Physical
activity in combination with a healthy diet pattern is recommended for older adults. While
aerobic type exercise is the most commonly recommended, retention of lean mass via resistance
training, especially in older adults, may be more effective at improving mobility,
neurological and psychological function, executive and cognitive functioning, and processing
speed. TRE combined with physical activity has not been examined in older adults or in people
with overweight or obesity. This study holds the potential to 1) decrease body weight 2)
improve lean mass 3) improve insulin sensitivity, and 4) improve attention, executive
functioning, and processing speed in older adults. The aims of this study will examine the
effect of TRE combined with either resistance training or aerobic training on body weight,
body composition, metabolic disease risk, and cognition in adults over age 50. It is
hypothesized that the TRE combined with resistance training group will see the most
significant improvements in body composition, insulin sensitivity and cognition due to lean
mass accretion.
Description:
Time restricted eating (TRE) is currently the most popular form of intermittent fasting which
involves confining the eating window to 8-10 hours (h) and fasting for the remaining hours of
the day. TRE is unique in that during the eating window, individuals are not required to
count calories or monitor food intake in any way, resulting in high adherence. Accumulating
evidence suggests that TRE produces a natural energy deficit of ~350-500 kcal/d. Physical
activity in combination with a healthy diet pattern is recommended for older adults. While
aerobic type exercise is the most commonly recommended, retention of lean mass via resistance
training, especially in older adults, may be more effective at improving mobility,
neurological and psychological function, executive and cognitive functioning, and processing
speed. T TRE combined with physical activity has not been examined in older adults or in
people with overweight or obesity. This study holds the potential to 1) decrease body weight
2) improve lean mass 3) improve insulin sensitivity, and 4) improve attention, executive
functioning, and processing speed in older adults. This study will examine the effect of TRE
combined with either resistance training or aerobic training on body weight, body
composition, metabolic disease risk, and cognition in adults over age 50. It is hypothesized
that the TRE combined with resistance training group will see the most significant
improvements in body composition, insulin sensitivity and cognition due to lean mass
accretion.