Aquatic Exercise for Cognition and Mobility in Older Adults

Cognitive Change Clinical Trial

Official title:

Effects of Aquatic Integrated Cognitive Motor Training on Cognition and Mobility in Older Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05501249
• Other study ID #: STUDY00001403
• Status: Completed
• Phase: N/A
• Start date: February 1, 2022
• Est. completion date: December 12, 2022

Study information

• Verified date: February 2023
• Source: University of Texas at Austin
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of this study is to assess the effects of an aquatic exercise program on cognition and physical function of older adults.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 25
• Est. completion date: December 12, 2022
• Est. primary completion date: December 12, 2022
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 65 Years and older

Eligibility

Inclusion Criteria:

• Able to ambulate 100 ft independently with or without assistive device
• Score greater than or equal to 3 on the Mini-Cog Test
• Stable medical condition within one month prior to the study
• Stable exercise program within one month prior to the study
• Available during study testing and group class times
• COVID-19 vaccination
• Permission from medical provider to participate in the study

Exclusion Criteria:

• History of dementia or Alzheimer's
• Contraindication to exercise or pool immersion (e.g., unstable cardiovascular conditions, fever, diarrhea, aqua-phobia)

Related Conditions & MeSH terms

• Aging Problems
• Aging Well
• Cognitive Change
• Gait Disorders, Neurologic
• Gait, Unsteady
• Mobility Limitation

Intervention

Behavioral:
• Aquatic Integrated Cognitive Motor Training
Aquatic exercise class with focus on cognitive and physical exercise

Locations

Country	Name	City	State
United States	The University of Texas at Austin	Austin	Texas

Sponsors (1)

Lead Sponsor	Collaborator
Emily Dunlap

Country where clinical trial is conducted

United States, 

References & Publications (10)

Bressel E, Louder TJ, Raikes AC, Alphonsa S, Kyvelidou A. Water Immersion Affects Episodic Memory and Postural Control in Healthy Older Adults. J Geriatr Phys Ther. 2019 Oct/Dec;42(4):E1-E6. doi: 10.1519/JPT.0000000000000192. — View Citation

Carter HH, Spence AL, Pugh CJ, Ainslie P, Naylor LH, Green DJ. Cardiovascular responses to water immersion in humans: impact on cerebral perfusion. Am J Physiol Regul Integr Comp Physiol. 2014 May;306(9):R636-40. doi: 10.1152/ajpregu.00516.2013. Epub 2014 Feb 19. — View Citation

Commandeur D, Klimstra MD, MacDonald S, Inouye K, Cox M, Chan D, Hundza SR. Difference scores between single-task and dual-task gait measures are better than clinical measures for detection of fall-risk in community-dwelling older adults. Gait Posture. 2018 Oct;66:155-159. doi: 10.1016/j.gaitpost.2018.08.020. Epub 2018 Aug 23. — View Citation

de Assis GG, de Almondes KM. Exercise-dependent BDNF as a Modulatory Factor for the Executive Processing of Individuals in Course of Cognitive Decline. A Systematic Review. Front Psychol. 2017 Apr 19;8:584. doi: 10.3389/fpsyg.2017.00584. eCollection 2017. — View Citation

Doi T, Shimada H, Makizako H, Tsutsumimoto K, Hotta R, Nakakubo S, Suzuki T. Association of insulin-like growth factor-1 with mild cognitive impairment and slow gait speed. Neurobiol Aging. 2015 Feb;36(2):942-7. doi: 10.1016/j.neurobiolaging.2014.10.035. Epub 2014 Nov 1. — View Citation

Kang DW, Bressel E, Kim DY. Effects of aquatic exercise on insulin-like growth factor-1, brain-derived neurotrophic factor, vascular endothelial growth factor, and cognitive function in elderly women. Exp Gerontol. 2020 Apr;132:110842. doi: 10.1016/j.exger.2020.110842. Epub 2020 Jan 15. — View Citation

Nissim M, Hutzler Y, Goldstein A. A walk on water: comparing the influence of Ai Chi and Tai Chi on fall risk and verbal working memory in ageing people with intellectual disabilities - a randomised controlled trial. J Intellect Disabil Res. 2019 Jun;63(6):603-613. doi: 10.1111/jir.12602. Epub 2019 Feb 18. — View Citation

Parfitt R, Hensman MY, Lucas SJE. Cerebral Blood Flow Responses to Aquatic Treadmill Exercise. Med Sci Sports Exerc. 2017 Jul;49(7):1305-1312. doi: 10.1249/MSS.0000000000001230. — View Citation

Pugh CJ, Sprung VS, Ono K, Spence AL, Thijssen DH, Carter HH, Green DJ. The effect of water immersion during exercise on cerebral blood flow. Med Sci Sports Exerc. 2015 Feb;47(2):299-306. doi: 10.1249/MSS.0000000000000422. — View Citation

Sato D, Seko C, Hashitomi T, Sengoku Y, Nomura T. Differential effects of water-based exercise on the cognitive function in independent elderly adults. Aging Clin Exp Res. 2015 Apr;27(2):149-59. doi: 10.1007/s40520-014-0252-9. Epub 2014 Jun 26. — View Citation

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Stroop Effect Test: Change from baseline to the end of intervention/control period	Measure of working memory and attention	Measures taken at baseline and again at approximately 9-10 weeks
Primary	Trail Making Test A and B: Change from baseline to the end of intervention/control period	Measure of visual scanning and working memory	Measures taken at baseline and again at approximately 9-10 weeks
Primary	Digit Backwards Test : Change from baseline to the end of intervention/control period	Measure of working memory capacity	Measures taken at baseline and again at approximately 9-10 weeks
Primary	Gait Measurements: Change from baseline to the end of intervention/control period	4 gait conditions (single task gait, dual task gait with head turns, dual task gait with head nods, and dual task gait count backwards by serial 7s). Gait measures collected with Strideway Gait Analysis System.	Measures taken at baseline and again at approximately 9-10 weeks
Primary	Functional Outcome Measures: Change from baseline to the end of intervention/control period	Timed Up and Go Test, Cognitive Timed Up and Go Test, Single Leg Balance Test, and Four Square Step Test.	Measures taken at baseline and again at approximately 9-10 weeks
Secondary	Vital Sign measurements: Change from baseline to the end of intervention/control period	Blood pressure and heart rate taken after 5 min supine, immediately upon standing, and 2 min after standing	Measures taken at baseline and again at approximately 9-10 weeks
Secondary	Anthropometric measurements: Change from baseline to the end of intervention/control period	Height and weight	Measures taken at baseline and again at approximately 9-10 weeks
Secondary	Neurotrophic Growth Factors: Change from baseline to the end of intervention/control period	Serum concentration of brain derived neurotrophic factor and insulin-like growth factor 1	Measures taken at baseline and again at approximately 9-10 weeks
Secondary	Numeric Pain Rating Scale: Change from baseline to the end of intervention/control period	An 11 point scale for level of pain from 0 (no pain) to 10 (severe pain).	Measures taken at baseline and again at approximately 9-10 weeks
Secondary	Global Rating of Change Questionnaire: Change from baseline to the end of intervention/control period	A 15 point global rating scale for changes in domains, from -7 (a great deal worse); through 0 (no change) to +7 (a great deal better).	Measures taken at baseline and again at approximately 9-10 weeks
Secondary	Activities-specific balance confidence scale: Change from baseline to the end of intervention/control period	A structured questionnaire that measures an individuals confidence performing daily activities. The minimum score is 0% (no confidence in balance) to 100% (complete confidence in balance).	Measures taken at baseline and again at approximately 9-10 weeks