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Clinical Trial Summary

The goal of this clinical trial is to determine whether there are any interactions between the study drug and cocaine. Researchers will compare a treatment group and a placebo group to see if they experience any effects when administered cocaine after taking the treatment/placebo.


Clinical Trial Description

This is a double-blind, placebo-controlled, parallel group study to compare the effects of SXC-2023 versus placebo control on intravenous cocaine's physiological and subjective effects in non-treatment seeking cocaine-experienced volunteers. Participants will be 18 to 59 years of age who have used cocaine by the smoked or intravenous route at least 6 times in the past 12 months prior to clinic intake, with at least one use within the past 3 months. Approximately twenty participants will be randomized to 2 groups, receiving either SXC-2023 or placebo treatment for 7 days. Adverse events and cardiovascular responses will be measured. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT06343532
Study type Interventional
Source National Institute on Drug Abuse (NIDA)
Contact Debra Kelsh, MD
Phone 913-696-1601
Email DKelsh@altasciences.com
Status Not yet recruiting
Phase Phase 1
Start date June 2024
Completion date December 2024

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