Prize Contingency Management for Cocaine-Dependent Methadone Patients

Status Completed

Clinical Trial Summary

The investigators will randomize 300 cocaine-dependent methadone patients to 1 of 6 conditions: (a) a control group, (b) a contingency management condition that arranges a 100% probability of winning a prize with each draw and has 3 prize categories, (c) a contingency management condition that arranges a 31% probability of winning and has 3 prize categories, (d) a contingency management condition that arranges a 100% probability of winning and has 7 prize categories, (e) a contingency management condition that arranges a 31% probability of winning and has 7 prize categories, or (f) usual prize contingency management with a 50% probability of winning from 3 prize categories. Magnitudes of reinforcement will be identical across conditions, but lower overall probability conditions arrange for greater chances of winning larger magnitude prizes. The investigators expect that the new contingency management conditions will reduce cocaine use relative to the control condition, that 31% probability conditions will decrease drug use relative to 100% conditions, and that 7-prize category conditions will reduce drug use compared to 3-prize category conditions. In addition, the 31%/7-category condition is expected to be most efficacious. Results will be instrumental for further developing prize contingency management to improve outcomes of cocaine-dependent methadone patients.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT01401270
Study type	Interventional
Source	UConn Health
Contact
Status	Completed
Phase	N/A
Start date	November 2011
Completion date	May 2018

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT01601743` - Exercise as a Behavioral Treatment for Cocaine Dependence	N/A
Completed	`NCT00217997` - Impulsivity, Brain Function, and Substance Abuse Treatment in Cocaine Dependent Individuals	N/A
Terminated	`NCT00142883` - The Effects of GABA Enhancing Medications on Individuals Addicted to Cocaine - 3	N/A
Completed	`NCT00842517` - Long Term Maintenance of Drug Abstinence	Phase 1
Completed	`NCT00227903` - Therapeutic Substance Abuse Treatment in Pregnancy - 1	Phase 2
Completed	`NCT02563769` - Clavulanic Acid (CLAV) and Cocaine Interaction Safety Study	Phase 1
Completed	`NCT01651377` - Pramipexole as a Treatment for Cocaine Dependence	Phase 1
Recruiting	`NCT00439049` - Substance Abuse Pre-Treatment Screening Study
Completed	`NCT00249457` - Employment-based Reinforcement to Motivate Drug Abstinence in the Treatment of Drug Addiction. - 2	N/A
Completed	`NCT00350610` - Computer-Based Training in Cognitive Behavior Therapy	Phase 1
Recruiting	`NCT06177860` - Clinical and Atherosclerotic Characteristics of Patients With ACS Associated With Cocaine Use
Completed	`NCT02393599` - Study to Assess Potential Interactions Between Intravenous Cocaine and Oral Lorcaserin	Phase 1
Completed	`NCT02141620` - n-Acetylcysteine and Cocaine	Phase 0
Recruiting	`NCT00218023` - Medications for Stopping Cocaine Dependence and Preventing Relapse	Phase 2
Completed	`NCT00218075` - Behavioral Therapy Combined With Carbidopa/Levodopa for the Treatment of Cocaine Dependence	Phase 2
Recruiting	`NCT05857852` - Low-Intensity Focused Ultrasound for Cocaine Use Disorder	N/A
Completed	`NCT00606801` - Galantamine Effects on Cognitive Function in Abstinent Cocaine Users	N/A
Completed	`NCT00292123` - Combined Behavioral and Pharmacologic Treatment of Polydrug Abuse	Phase 1
Completed	`NCT00318760` - Effect of Clonidine on Responses to Imagery Scripts	Phase 1
Completed	`NCT01651364` - A Pilot Study of Cabergoline for the Treatment of Cocaine Dependence	Phase 1