Cocaine Abuse Clinical Trial
Official title:
Maximizing the Efficacy of Cognitive Behavioral Therapy With Medication and Contingency Management
This is a study of four treatments for chronic cocaine use and may help study participants to control their drug use. All participants will receive weekly individual cognitive behavioral therapy (CBT).
This study will compare four types of treatment involving skills training and incentives for
attending sessions or taking study medication. Disulfiram is a widely prescribed deterrent
to alcohol use. In addition to weekly cognitive behavioral therapy (CBT), participants will
be assigned to one of the following treatments:
1. placebo
2. disulfiram
3. placebo plus incentives for cocaine abstinence and medication compliance (prize CM)
4. disulfiram plus incentives for cocaine abstinence and medication compliance
;
Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Factorial Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Treatment
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