CNS Viral Infection Clinical Trial
— VIMPACOfficial title:
Cerebrospinal Fluid Polymerase Chain Reaction Arrays for Central Nervous System Neurotropic Viral Infection and Mycobacterium Infection Study
| Verified date | May 2010 |
| Source | Rajavithi Hospital |
| Contact | n/a |
| Is FDA regulated | No |
| Health authority | Thailand: Ministry of Public Health |
| Study type | Observational |
This study of neurotropic viral infection and Tuberculous CNS infection is the comprehensive
investigation of CSF PCR arrays (Hybrydiaztion technique,Sybergreen and Taqman real time PCR
arrays of CSF ) in suspected cases of viral CNS infection, Tuberculous CNS infection in both
AIDS and non AIDS patients.
Patients with clinical viral encephalitis and all meningoencephalitis including all patients
with HIV/AIDS CSF and non AIDS will be banked and test for RNA and DNA viral sequence by
Real time PCR arrays and IS6110 gene of Mycobacterium tuberculosis. Clinical data and final
diagnosis will be used to analyze the result of this PCR arrays technique compared to
clinical gold standard criteria.
| Status | Completed |
| Enrollment | 200 |
| Est. completion date | March 2010 |
| Est. primary completion date | December 2009 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 15 Years and older |
| Eligibility |
Inclusion Criteria: 1. AGE MORE THAN 15 YRS 2. ABLE TO INFORM CONSENT BY THEMSELF OR THEIR PARENT 3. SUSPECTED CNS VIRAL INFECTION Exclusion Criteria: 1. UNABLE/CONTRAINDICATED FOR LUMBAR PUNCTURE OR CSF COLLECTION 2. WITHDRAW CONSENT 3. SUSPECTED SEVERE OR VILURENT VIRAL INFECTION SUCH AS H5N1/SARS INFECTION |
Observational Model: Case-Only, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| n/a | |||
| Lead Sponsor | Collaborator |
|---|---|
| Rajavithi Hospital | Rajavithi Biomolecular Research Center |