Effect of Orthoses and Underfoot Vibration on Balance in Neuropathy

Peripheral Neuropathy Clinical Trial

Official title: The Feasibility and Effect of Ankle Foot Orthoses and Underfoot Vibration on the Postural Stability of People With Inherited Neuropathy

Status Recruiting

Clinical Trial Summary

A cross-sectional study which will look at the effects of AFO's and vibrating insoles on balance performance in people with CMT disease.

Clinical Trial Description

Balance impairments and falls are more common in people who have Charcot Marie Tooth disease (CMT) than in people without the condition. CMT is a condition which affects the nerves causing a variety of symptoms including sensation impairments and weakness. The impairments are usually most evident in the feet and hands, but they can progress very slowly moving closer to the trunk. Ankle Foot Orthoses (AFO's) are often prescribed to help with walking and daily function. So far the effects of AFO's on standing balance in people who have CMT have not been looked at. Insoles are also often prescribed to realign foot deformity and reduce pain. Insoles which give a vibratory input have had a positive impact on walking in older people but have not been looked at in balance and in CMT. Insoles which give a vibration feedback to the sole of the foot when worn have been designed. This study will look at whether the use of AFO's and the vibratory insoles have an effect on standing balance in people with CMT or related peripheral neuropathy. Balance measurements will be taken in a single session comparing a variety of postures. Patients will be recruited from neurology outpatient clinics at the National Hospital of Neurology and Neurosurgery. ;

Related Conditions & MeSH terms

• Charcot-Marie-Tooth Disease
• CMT - Charcot-Marie-Tooth Disease
• CMT1A
• Hereditary Peripheral Neuropathy
• Hereditary Sensory and Motor Neuropathy
• Nerve Compression Syndromes
• Peripheral Nervous System Diseases
• Peripheral Neuropathy
• Tooth Diseases

• NCT number: NCT03278093
• Study type: Observational
• Source: St George's, University of London
• Contact: Magdalena Dudziec
• Phone: 020 3108 7520
• Email: m.dudziec@ucl.ac.uk
• Status: Recruiting
• Start date: October 20, 2017
• Completion date: February 20, 2019