Clostridium Difficile Infection Clinical Trial
Official title:
Validation of a Prediction Score for Recurrent C. Difficile Infection: Implementation for Treatment Algorithm Strategies
The objective of the present study is to derive a high-risk R-ICD prediction rule and a prospective implementation of this prediction rule.
For objectives 1 and 2, a retrospective study of the microbiology database will be carried
out and the medical records will be consulted to collect the variables included in Annex 2.
The other prediction rules to be compared are those of Cobo et al., Reigadas et al and
Gerding et al.
We will review a total of 215 patients according to the calculation of the sample size (see
section) A prospective study will also be carried out in which the positive patients for C.
difficile determined by the Microbiology Service of the General University Hospital Gregorio
Marañón will be included. The medical records of the selected cases will be reviewed. All
patients included in the prospective study (Objective 3) will receive the information sheet
and consent sheet that they must sign for this study (Annex 1). These patients will be
followed and the variables included in Annex 2 will be collected.
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