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Clinical Trial Summary

This is a single arm, open-label, multi-center, phase I/II study to determine the engraftment, safety and clinical activity of allogeneic CARCIK-CD19 cells in adult and pediatric patients with relapsed/refractory mature B-cell neoplasia expected to express CD19 i.e. B-cell NHL and CLL. CARCIK-CD19 will be produced from the peripheral blood of an at least haploidentical familial donor.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05869279
Study type Interventional
Source Fondazione Matilde Tettamanti Menotti De Marchi Onlus
Contact Andrea Biondi, MD
Phone +39039233
Email segreteriadirezionecp@fondazionembbm.it
Status Recruiting
Phase Phase 1/Phase 2
Start date December 1, 2023
Completion date September 1, 2027

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