Interscalene vs. Superficial Cervical Block vs. Combination for Analgesia

Status Recruiting

Clinical Trial Summary

The optimal analgesic peripheral nerve block (or combinations thereof) are undefined for clavicle fractures, the most frequent fracture in the human population. This goal of this study is to determine whether interscalene block (ISB), superficial cervical plexus block (SCPB), or both provide the best analgesia for lateral and midshaft clavicular fractures, respectively.

Clinical Trial Description

Clavicle fractures are relatively common injuries that occur most often in young active males and elderly individuals. They are often a result of direct trauma to the shoulder, typically from a fall. Clavicle fractures represent 5-10% of all fractures and represent the most frequent fracture in the human population. Midshaft fractures account for 69-85% of the clavicle fractures, distal shaft fractures 12-28%. (1) Analgesia for clavicle fractures can be challenging for anaesthetists secondary to the complex and varied innervation in this region. Literature describing the innervation of the clavicle and overlying skin is heterogeneous with the C3 to C6 nerve roots being involved. The clavicle itself has been reported to be innervated either by C4 or by C5 and C6 (subclavian nerve) nerve roots. (2) Regional anaesthesia for intraoperative and postoperative analgesia of clavicle fractures employs several possible, commonly used approaches. The contemporary literature surrounding the optimal regional anaesthetic technique for clavicle surgery which can provide superior postoperative analgesia and minimize systemic agents intraoperatively is lacking Currently there are only small case series or case reports published. Peripheral nerve blocks used to anesthetize the clavicle include SCPB, ISB, and combined SCPB-ISB. Larger, systematic trials have not yet been performed to our knowledge and as recently as one year ago a call for more evidence in this area of regional anaesthesia was published in the American Society of Regional Anesthesia and Pain Medicine. The purpose of this study is to compare analgesic outcomes after the common regional anesthetic techniques (ISB versus SCPB versus both). ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03094481
Study type	Interventional
Source	Sunnybrook Health Sciences Centre
Contact	Paul McHardy, MD, FRCPC
Phone	4164804864
Email	paul.mchardy@sunnybrook.ca
Status	Recruiting
Phase	N/A
Start date	October 21, 2016
Completion date	March 1, 2020

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT04161534` - KT Tape for Pediatric Clavicle Fractures	N/A
Completed	`NCT06050473` - Supraclavicular Nerve During Clavicle ORIF	N/A
Not yet recruiting	`NCT05262998` - Intramedullary Screw Versus Plate in Displaced Midshaft Clavicle Fractures	N/A
Not yet recruiting	`NCT05579873` - Double Plating Versus Single Plating Techniques in Midshaft Clavicle Fractures
Completed	`NCT02769117` - Bone Ultrasound to Access Fracture Healing	N/A
Withdrawn	`NCT04986553` - A Multi-Center, Prospective Registry to Evaluate the Continued Safety and Performance of Clavicle Plates
Recruiting	`NCT05810129` - Crossed Education in Relation to Muscle Mass in Patients Operated of Clavicular Fracture	N/A
Enrolling by invitation	`NCT05327959` - A.L.P.S. Clavicle Plating System PMCF	N/A
Recruiting	`NCT05867355` - Surgically Treated Displaced Mid-diaphyseal Clavicle Fractures
Completed	`NCT00872105` - Conservative Treatment Versus Operative Plate Fixation for Acute, Displaced Fractures of the Distal Clavicle	N/A
Withdrawn	`NCT00849771` - Operative Versus Nonoperative Treatment for Scapula Fractures	N/A
Completed	`NCT05268874` - The Effectiveness of Clavipectoral Fascia Plane Block for Clavicle Surgery	N/A
Recruiting	`NCT04250415` - Multi-Center Adolescent Clavicle Fracture Trial: Operative vs. Non-Operative Treatment
Withdrawn	`NCT01133769` - Operative Versus Non-Operative Treatment of Clavicle Fracture in PolyTrauma	N/A
Completed	`NCT06269562` - SPSIPB and CPB on Clavicle Surgeries	N/A
Completed	`NCT01405703` - Percutaneous Versus Open Plate Fixation of Diaphyseal Clavicle Fractures	N/A
Completed	`NCT01410032` - Reconstruction Plate Compared With Flexible Intramedullary Nailing for Midshaft Clavicular Fractures	Phase 2
Suspended	`NCT05454306` - Anser Clavicle Pin for Surgical Management of Midshaft Clavicle Fractures	N/A
Completed	`NCT03402269` - Treatment of Pediatric Mid-shaft Clavicle Fractures: A Prospective, Observational Study
Active, not recruiting	`NCT04622137` - Kinesiotaping Therapy for Clavicular Fractures FRACTURES:	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

Interscalene vs. Superficial Cervical Block vs. Combination for Analgesia After Clavicle Fracture

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms