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NCT04915573 Clinical Trial

Antimicrobial Resistance in Cirrhotic Patients

Cirrhosis Clinical Trial

Official title:
Antimicrobial Resistance Among Sputum Pathogens in Post Hepatitis Cirrhotic Patients

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT04915573
Other study ID # 34647/4/21
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date June 7, 2021
Est. completion date September 2021

Study information
Verified date June 2021
Source Mansoura University
Contact Noha Mansour, Ph.D
Phone 0020403315352
Email dr.nohamansour@gmail.com
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Cirrhotic patients are more vulnerable to bacterial infection, and infection is one of the most common causes of acute liver disease decompensation.

Description:

Cirrhotic patients are more vulnerable to bacterial infection which is a common cause of acute liver disease decompensation. The aim of this study will characterize the antimicrobial resistance and distribution of bacteria isolated from chronic hepatic patients with pulmonary infections, as well as to evaluate the antimicrobial susceptibility of bacteria isolated from sputum.

Recruitment information / eligibility
Status Recruiting
Enrollment 100
Est. completion date September 2021
Est. primary completion date September 2021
Accepts healthy volunteers
Gender All
Age group 18 Years and older
Eligibility Inclusion Criteria: 1. Adults' older than 18 years with clinical evidence of liver disease Exclusion Criteria: 1. Pregnancy 2. Intensive care unite stay of more than 24 hours 3. Malignancy 4. Organ transplantation 5. Acquired immune deficiency syndrome

Study Design

Related Conditions & MeSH terms

Intervention

Diagnostic Test:
• Specimen
Sputum will be collected in clean disposable containers

Locations
Country Name City State
Egypt Tanta University Hospitals Tanta

Sponsors (2)
Lead Sponsor Collaborator
Mansoura University Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Isolate Identification Distribution of bacterial isolates from sputum of cirrhotic patients expressed by frequency of each isolate One day
Primary Antimicrobial resistance Antimicrobial susceptibility testing to antibiotics determined by kirby-bauer disk diffusion One day
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