Cirrhosis Clinical Trial
There are several factors that influence telomere length in patients with cirrhosis, such as metabolic derangements and infectious etiologies, The aim of the study is to compare telomere length and other parameters related to genetic instability in telomere/ telomerase system, in peripheral blood lymphocytes in cirrhosis from different etiologies.
| Status | Recruiting |
| Enrollment | 50 |
| Est. completion date | December 2015 |
| Est. primary completion date | December 2015 |
| Accepts healthy volunteers | No |
| Gender | Both |
| Age group | 18 Years and older |
| Eligibility |
Inclusion Criteria: - cirrhotic patients from different etiologies Exclusion Criteria: - decompensated cirrhosis (Child C) - age under 18 years - any known malignancy, including hepatocellular carcinoma - patient that are unable to sign for informed consent |
Observational Model: Case-Only, Time Perspective: Prospective
| Country | Name | City | State |
|---|---|---|---|
| Israel | Meir Medical Center | Kfar Saba |
| Lead Sponsor | Collaborator |
|---|---|
| Meir Medical Center |
Israel,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | telomerase activity | number of copies of telomerase in peripheral blood lymphocytes, as determined by FISH | baseline | No |
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