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NCT05828836 Clinical Trial

Allopurinol and Quality of Life in Liver Cirrhosis

Cirrhosis, Liver Clinical Trial

Official title:
the Impact of Allopurinol of HRQOL in Cirrhotic Patients

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT05828836
Other study ID # AqOL
Secondary ID
Status Completed
Phase Phase 2/Phase 3
First received
Last updated
Start date June 15, 2022
Est. completion date March 1, 2023

Study information
Verified date October 2023
Source Tanta University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The study aims to evaluate the impact of allopurinol on patients' related quality of life.

Description:

Cirrhosis is the late stage of liver damage and possess two phases:. The shift from compensated to decompensated cirrhosis is characterized by the onset of complications) which are associated with substantial morbidity and negative Impact on quality of life (QOL)Cirrhosis and its complications have a substantial economic, social, and personal impact on affected patients, as well as their families and caregivers

Recruitment information / eligibility
Status Completed
Enrollment 100
Est. completion date March 1, 2023
Est. primary completion date January 15, 2023
Accepts healthy volunteers No
Gender All
Age group 18 Years to 70 Years
Eligibility Inclusion Criteria: cirrhosis adult both sex Exclusion Criteria: - renal insufficiency

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• Allopurinol Tablet
allopurinol300mg once daily
• Placebo
placebo once daily

Locations
Country Name City State
Egypt Faculty of Pharmacy Tanta

Sponsors (1)
Lead Sponsor Collaborator
Tanta University

Country where clinical trial is conducted

Egypt, 

Outcome
Type Measure Description Time frame Safety issue
Primary Chronic liver disease questionnaire effect on Chronic liver disease questionnaire score 6 months
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