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The Utility of Breath Biopsy as a Screening Tool for HCC — BrtH-C  

Cirrhosis, Liver Clinical Trial

Official title:
The Utility of Breath Biopsy as a Screening Tool for HCC: A Pilot Study

Clinical Trial Summary

The aim of this pilot study is to examine whether there is a discriminating ability of the breath sample analysis to capture biomarkers specific to the HCC in the breath of affected individuals. If positive, our research could open up a new horizon for cost-effective and feasible screening tools.

Clinical Trial Description

20 Participants will be included in the study. Ten Cirrhotic patients with HCC and 10 Cirrhotic patients without HCC. The first group is patients with HCC secondary to cirrhosis. The second group will be patients with cirrhosis who are currently on the standard surveillance program with no HCC. Confirmation of the absence of HCC would have been ensured via a recent advanced imaging modality (dynamic CT scan or MRI) in the ongoing surveillance programme. Participants will breathe into either a mouthpiece or collection tube then Breath samples will be analyzed via an analyzer to detect the volatile organic compounds (VOC) and quantitatively compare them ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04326491
Study type Observational
Source University of Aberdeen
Contact
Status Completed
Phase
Start date June 20, 2021
Completion date May 16, 2022
View Details
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