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NCT06068348 Clinical Trial

Liquid Biopsy Collection Study

Circulating Tumor Cells Clinical Trial

Official title:
Collection of Human Blood for Development of Liquid Biopsy Assay

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT06068348
Other study ID # STUDY00003221
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date October 7, 2021
Est. completion date October 2024

Study information
Verified date November 2023
Source University of Central Florida
Contact Amoy Fraser, PhD, CCRP, PMP
Phone 407-266-8742
Email amoy.fraser@ucf.edu
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

The purpose of this study is to develop a liquid biopsy approach for detection of circulating tumor cells (CTC) that could be used in place of the more invasive and potentially risky methods of tissue biopsy. The aims of the project are: (a) determine whether the Chaperonin-Containing TCP-1 (CCT) chaperonin can used to identify rare cancer cells in blood, and (b) establish whether the cancer cells detected using the CCT chaperonin for identification have invasive or metastatic potential.

Recruitment information / eligibility
Status Recruiting
Enrollment 60
Est. completion date October 2024
Est. primary completion date October 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 80 Years
Eligibility Inclusion Criteria: - Male or female - Age greater than or equal to 18 and less than or equal to 80 years. Exclusion Criteria: - Adults unable to give informed consent - Individuals who are not yet adults (infants, children, teenagers; under the age of 18) - Individuals who weigh less than 110 lbs (as standard clinically advised to not give blood) - Pregnant women (due to hormonal changes in blood) - Prisoners - Persons reporting a current microbial (bacterial, viral, or fungal) infections - Persons reporting that they are current taking antibiotic medications - Persons with body temperatures above 99oF (indicating a fever)

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
United States University of Central Florida Orlando Florida

Sponsors (1)
Lead Sponsor Collaborator
University of Central Florida

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary To determine if the biomarker, Chaperonin-Containing TCP-1 (CCT), can be used to detect circulating tumor cells (CTC) in blood. 3 years
Secondary To determine if the CCT chaperonin can provide information on the metastatic potential of CTC. 3 years
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