Cigarette Smoker Clinical Trial
Official title:
Effects of Filter Ventilation on Sensory Response, Smoking Topography, and Inhalation (COMET 2 2.1)
Verified date | July 2022 |
Source | Roswell Park Cancer Institute |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Observational |
This trial examines the effects of filter ventilation on sensory response, smoking topography, and inhalation in current every day cigarette smokers. The physical design features of cigarettes directly impact their appeal by influencing cognitive and sensory perceptions. The introduction of a now common design feature, filter ventilation, has led to greater public harm than benefit because of the potential for greater toxicity while enhancing product appeal among smokers. Ventilated cigarettes dilute smoke, which promotes perceptions of ?smoothness? and therefore lower health risk, contributing to the overall appeal of these products. The purpose of this study is to assess whether removing ventilation from cigarette filters lowers cigarette product appeal among smokers.
Status | Completed |
Enrollment | 8 |
Est. completion date | March 2, 2020 |
Est. primary completion date | March 2, 2020 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 69 Years |
Eligibility | Inclusion Criteria: - Currently smoking daily at least 5 cigarettes per day for at least one year - Primarily using factory-made filtered cigarettes with filter ventilation - Fair and above physical health - Fair and above mental health - Not actively trying to quit smoking or planning to quit in the next 30 days - Able to converse, read, and write in English - No alcohol or illegal drug use - Not pregnant or breastfeeding Exclusion Criteria: - Currently smoking daily less than 5 cigarettes per day for at least one year - Using roll-your-own cigarettes or unventilated filter cigarettes - Currently using any other tobacco product daily - Actively trying to quit smoking or planning to quit in the next 30 days - Not able to converse, read, and write in English - Adults unable to consent - Prisoners - Poor physical health by self report - Poor mental health by self report - Alcohol and illegal drug use - Pregnant or breastfeeding by self report |
Country | Name | City | State |
---|---|---|---|
United States | Roswell Park Cancer Institute | Buffalo | New York |
Lead Sponsor | Collaborator |
---|---|
Roswell Park Cancer Institute | National Cancer Institute (NCI), University of Minnesota |
United States,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Modified Cigarette Evaluation Questionnaire | Scored using an established algorithm. This results in 3 subscales (psychological reward, relief, reward) and 2 single items (aversion, respiratory sensation). | Up to 210 minutes | |
Secondary | Carbon monoxide (CO) boost | Defined as the difference between pre-smoking exhaled CO and postsmoking exhaled CO. | Up to 210 minutes |
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