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Cicatrix clinical trials

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NCT ID: NCT01494922 Completed - Clinical trials for Reduction in Severity of Skin Scarring

Safety and Efficacy of EXC 001 in Subjects Who Have Participated in Prior Studies of EXC 001

Start date: December 8, 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to provide subjects who participated in prior studies of EXC 001 the opportunity to have their hypertrophic scars surgically revised and treated with EXC 001.

NCT ID: NCT01488240 Recruiting - Burn Scar Clinical Trials

The Role of Pulsed Dye Laser Therapy in the Management of Burn Scars

Start date: November 1, 2012
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the effects (good or bad) of pulsed dye laser treatment in burn scar height, texture, redness and pliability in acute burn injury.

NCT ID: NCT01433198 Withdrawn - Burns Clinical Trials

Aquatic Training in Patients With Severe Scarring

Start date: May 2018
Phase: N/A
Study type: Interventional

Aim: - to investigate the effects of an aquatic exercise program in patients with severe scars Patient population: - 10 patients of at least 18 years old - patients with scars after burns or other severe skin injuries - stratification into two groups: an intervention group and a control group Method: - 8 patients will participate in the aquatic exercise group and 2 patients in the control group - assessment of physical fitness parameters, scar tissue and psychosocial impact Hypothesis: - patients of the aquatic exercise group will recover sooner and better (physically and psychologically) than patients of the control group

NCT ID: NCT01409863 Withdrawn - Scar Clinical Trials

Fractional Laser Therapy and Dermabrasion for Scar Revision

Start date: March 2010
Phase: N/A
Study type: Interventional

The goals of this study will be to compare the safety and efficacy of fractional photothermolysis (Fraxel) with dermabrasion when used for scar revision.

NCT ID: NCT01346969 Completed - Clinical trials for Reduction in Hypertrophic Skin Scarring

Safety and Efficacy Study of EXC 001 to Improve the Appearance of Scars From Prior Breast Surgery

Start date: June 1, 2011
Phase: Phase 2
Study type: Interventional

The study will investigate the efficacy of various doses and regimens of EXC 001 in reducing skin scarring in subjects undergoing revision of scars from prior surgery. The study will also evaluate the safety and tolerability of EXC 001 and placebo.

NCT ID: NCT01264588 Completed - Wound Healing Clinical Trials

The Effects of Topical Calcium Glycerophosphate on Surgical Wound Healing and Residual Scarring

TOPCGP-2008
Start date: April 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to determine whether topical application of calcium glycerophosphate will result in superior wound appearance and scar minimization.

NCT ID: NCT01217567 Completed - Cesarean Section Clinical Trials

Subcuticular Suture Versus Staples for Closure of the Skin After Caesarean Section.

Start date: March 2010
Phase: N/A
Study type: Interventional

The Purpose of this study is to compare two methods for closure of the skin after caesarean section on the same patient; staples and subcuticular sutures. The study is performed on two separate groups of patients: 1. Woman having cesarean section for the first time and have not previously had abdominal surgery through a lower abdominal transverse incision. 2. Woman, who have previously had a caesarean section done. The following parameters are registered: 1. An objective evaluation of the two ends of the scar 6 months postoperatively. 2. A patient evaluation of the two ends of the scar 6 months postoperatively. 3. The difference in pain in the two ends of the scar 1 day postoperatively (blinded). 4. The difference in pain in the two ends of the scar 7 days, 3 and 6 months postoperatively. 5. The rate of infection.

NCT ID: NCT01213199 Completed - Acne Scars Clinical Trials

Adapalene Gel 0.3% in the Treatment of Atrophic Acne Scars

Start date: March 2011
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the efficacy and safety of Adapalene Gel 0.3% in the treatment of atrophic acne scars.

NCT ID: NCT01176448 Completed - Cicatrix Clinical Trials

Laser Resurfacing Versus Dermabrasion for Scar Revision

Start date: April 2010
Phase: N/A
Study type: Interventional

Dermabrasion has been the historical standard used for resurfacing scars on the skin. Recently, fractionated laser therapy has been FDA approved for scar resurfacing. This study intends to compare dermabrasion versus fractionated laser therapy for scar resurfacing.

NCT ID: NCT01115868 Active, not recruiting - Scarring Clinical Trials

Prevascar in African Continental Group Scarring

Start date: April 2010
Phase: Phase 1
Study type: Interventional

There is considerable variation in scarring, within and between people, and between different ethnic groups. Individuals with more pigmented skin are more prone to severe scarring than those traditionally termed white. Prevascar is being developed by Renovo for use as a potential treatment for reducing scarring. Renovo's histological analysis of wounds and scars in human non drug studies demonstrates an increase in wound and scar width in subjects of African Caribbean ancestry over a 12 month period. It is hypothesised that IL-10 may be a potentially beneficial therapy for the reduction of scarring in Non Caucasians of African-Caribbean ancestry. This Renovo clinical trial will be carried out primarily to establish the effects of four doses of Prevascar on 1cm incisional and excisional scars in subjects of African Continental Group ancestry, as compared to placebo, and to further investigate the safety and tolerance of intradermally injected Prevascar in wounds.