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Chronic Venous Insufficiency clinical trials

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NCT ID: NCT06232421 Not yet recruiting - Clinical trials for Chronic Venous Insufficiency

Clinical Study in Adult Patients With Purulent-inflammatory Processes of the Skin and Soft Tissues, Phase I-II of the Wound Process

OLENKRON-01
Start date: June 2024
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to estimate efficiency, tolerance, safety of "Foscelantan, medicinal plate 4.0x5.0 cm in package No. 1" among adult patients who have purulent-inflammatory processes of the skin and soft tissues due to the neuropathic form of diabetic foot syndrome or chronic venous insufficiency, phase I-II of the wound process.

NCT ID: NCT05993650 Not yet recruiting - Clinical trials for Chronic Venous Insufficiency

Inspiratory Muscle Training in Chronic Venous Diseases

Start date: August 2023
Phase: N/A
Study type: Interventional

There is insufficient evidence of inspiratory muscle training on venous function, clinical severity, symptoms and functional capacity and quality of life in CVI patients. Therefore, in the study, the investigators aimed to determine the effectiveness of inspiratory muscle training in individuals with chronic venous insufficiency.

NCT ID: NCT04794712 Not yet recruiting - Clinical trials for Chronic Venous Insufficiency

Evaluation of Pain Associated With Chronic Venous Insufficiency

Start date: May 15, 2021
Phase:
Study type: Observational [Patient Registry]

Chronic venous insufficiency occurs when your leg veins don't allow blood to flow back up to your heart. Normally, the valves in your veins make sure that blood flows toward your heart. But when these valves don't work well, blood can also flow backwards. This can cause blood to collect (pool) in the legs. Chronic venous disease is a highly prevalent condition in the general population, and it has a significant impact on quality of life. While it is usually manifested by obvious signs, such as varicose veins and venous ulcers, other symptoms of the disease are less specific. Among the other symptoms, which include heaviness, swelling, muscle cramps and restless legs, pain is the symptom that most frequently compels CVeD patients to seek medical aid. However, there is a substantial discrepancy between pain severity and clinically detectable signs of CVeD, questioned by several opposing studies. Further evaluation is needed to clarify this subject, and to analyse whether pain development predicts objective tool to evaluate pain by dosflexin exercise pre surgery and post and measure the severity of pain by heat stimulation . General management of CVeD starts with advising lifestyle . pain in chronic venous insufficiency it will measure before and after treatment by using contact heat evoked potential (CHEPS) and visual dialog scale ( VAS ) to estimate the pain intensity the severity of the pain before the patient do exercise before three moths of leaser endovenous ablation procedure . 2-photo-plethysomography Non invasive technique , pp sensor emit infrared light detects changes in reflection from epiderma layer . Vessels full of blood reflect 10 times less than without blood . On dorsiflexion - pressure drops, increasing reflection in the measuring window Venous assessment the venous refill time, is shorter and typically less than 20 s

NCT ID: NCT04339088 Not yet recruiting - Varicose Veins Clinical Trials

High Intensity Focused Ultrasound in PAtients With Varicose Veins in Singapore

VESPA
Start date: March 1, 2022
Phase:
Study type: Observational

The aim of the study is to evaluate the efficacy of non-invasive echotherapy for the treatment of varicose veins, within local population, using the Sonovein® device. The quality of life scores at baseline, 2 weeks, 3 months, 6 months and 12 months will be assessed using the EQ-50D, AVVQ and CIVIQ scores. Patient satisfaction at these time points will also be assessed.

NCT ID: NCT03384355 Not yet recruiting - Varicose Veins Clinical Trials

Ecchymosis and Coldness in Patients With Varicose Vein

VEIN-COLD
Start date: January 2018
Phase: N/A
Study type: Observational [Patient Registry]

In this prospective, observational study, the investigators aim to investigate the symptoms of varicose vein patients.

NCT ID: NCT02927483 Not yet recruiting - Clinical trials for Chronic Venous Insufficiency

Study to Assess the Efficacy and Safety of Endolex Forte VErsus Diosmin and Hesperidin in Reducing VeNous Insufficiency

EVELINE
Start date: November 2016
Phase: Phase 3
Study type: Interventional

The trial is designed as a randomized, multicenter, open label, comparative, 6 months, clinical study.

NCT ID: NCT01477281 Not yet recruiting - Clinical trials for Chronic Venous Insufficiency

Study to Evaluate the Efficacy and Tolerability of Venaflon Use in Reducing the Symptoms Caused by Chronic Venous Insufficiency When Compared With Daflon

Start date: February 2012
Phase: Phase 3
Study type: Interventional

The objective is to evaluate the effectiveness of the safety of Daflon in decreasing symptoms resulting from chronic venous insufficiency when compared with Daflon.

NCT ID: NCT01321619 Not yet recruiting - Hemorrhoids Clinical Trials

Efficacy and Tolerability of the Use of Varicell Compared With Daflon

Start date: July 2011
Phase: Phase 3
Study type: Interventional

The purpose of this study is to evaluate the efficacy and tolerability of Varicell compared to Daflon, in reducing the symptoms caused by chronic venous insufficiency and hemorrhoidal syndrome.