Brain Imaging Study of Brain Plasticity in Chronic Stroke Patients

Chronic Stroke Clinical Trial

Official title:

Functional Magnetic Resonance Imaging and Diffusion Tensor Imaging Study About Reorganization and Recovery Mechanism of Brain Neural Network for Chronic Stroke Patients

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03392519
• Other study ID #: 2015-07-082
• Status: Completed
• Start date: August 18, 2015
• Est. completion date: July 17, 2020

Study information

• Verified date: September 2019
• Source: Samsung Medical Center
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

In chronic stroke patients, brain network reorganization and recovery mechanism are investigated after stroke onset using functional MRI and diffusion tensor imaging analyses.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 59
• Est. completion date: July 17, 2020
• Est. primary completion date: June 30, 2020
• Accepts healthy volunteers: No
• Gender: All
• Age group: N/A and older

Eligibility

Inclusion Criteria:

• more than 3 months post-stroke

• ischemic or hemorrhagic stroke

• a person who understands the experiment and has a willingness to participate and signs the agreement

Exclusion Criteria:

• User of artificial heartbeat

• Patients with claustrophobia

• Patients with metal implants

• Patients who are contraindicated for other common MRI

Related Conditions & MeSH terms

• Chronic Stroke
• Stroke

Intervention

Other:
• Chronic stroke
MRI data acquisition and behavioral test

Locations

Country	Name	City	State
Korea, Republic of	Samsung Medical Center	Seoul

Sponsors (1)

Lead Sponsor	Collaborator
Samsung Medical Center

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Correlation coefficient between strength of connection and the Fugl-Meyer Assessment score	Strength of connection is obtained by calculating a correlation coefficient between time courses of both regions in fMRI data.	Through study completion, an average of 1 year
Primary	Correlation coefficient between the FA value of a tract and the Fugl-Meyer Assessment score	FA value is obtained by assessing a diffusion anisotropy of a specific tract in DTI data.	Through study completion, an average of 1 year