Clinical Trials Logo
  1. Home
  2. Chronic Respiratory Failure
  3. NCT01518439

Instrumental and Manual Increase of Couch in Neuromuscular Patients — OPTICOUGH  

Chronic Respiratory Failure Clinical Trial

Official title:
Instrumental and Manual Increase of Couch in Neuromuscular Patients: Effects of Different Techniques on the Generated Flow

Clinical Trial Summary

Inefficient cough is responsible of respiratory complications in neuromuscular patients which can lead to hospitalisation and can be life threatening. Techniques enhancing cough efficiency are successful in improving the clearance of bronchial secretions and help non invasive ventilation efficiency especially in case of acute respiratory failure. Combining mechanical exsufflation to the manual techniques of physiotherapy might enhance efficiency. Therefore the investigators want to compare cough efficiency under different techniques of instrumental and manual of cough assistance in order to determine the best combination to optimize cough flow.

Clinical Trial Description

Hypothesis: Cough inefficiency in neuromuscular patients increases morbidity and mortality in case of airway infections and may lead to invasive ventilation. The use of techniques enhancing cough have been successful in improving the success of non invasive ventilation. We want to determine whether adding manual physiotherapist techniques to mechanical exsufflation improve cough efficiency and its ability to clear bronchial secretions.

Objectives: To compare cough flows obtained with different combination of the use of increased inspiratory capacity technique, mechanical insufflation-exsufflation technique and manually applied pressures techniques.

Method:open monocentric cross-over study (the patients are their own controls). Five combinations of cough increase techniques are compared Inclusion criteria: adult neuromuscular patients with a cough inefficiency at a stable state upon inclusion.

As this is a pilot study, 20 patients from the home ventilation unit of the intensive care of the Raymond Poincare teaching hospital (Garches, France) will be included during the usual follow-up of chronic respiratory failure. ;

Study Design

Allocation: Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01518439
Study type Interventional
Source Centre d'Investigation Clinique et Technologique 805
Contact
Status Completed
Phase N/A
Start date January 2012
Completion date July 2013
View Details
See also
  Status Clinical Trial Phase
Completed NCT05084976 - Parental Perception of COVID-19 Vaccine in Technology Dependent Patients
Not yet recruiting NCT05756387 - Improving Chronic Nocturnal Noninvasive Ventilation: a Multimodality Approach
Enrolling by invitation NCT04208581 - Yiqi Huoxue Huatan Granule for Reducing Mortality in COPD With Chronic Respiratory Failure Phase 3
Recruiting NCT02260583 - Effect of Extracorporeal CO2 Removal in Stable Hypercapnic COPD Patients N/A
Completed NCT01255111 - Adaptation to Nocturnal Noninvasive Ventilation in Patients With Chronic Respiratory Failure (ROOMILA) N/A
Active, not recruiting NCT03499470 - Structured Discharge and Follow-up Protocol for COPD Patients Receiving LTOT and NIV N/A
Completed NCT04143230 - Identification of In-hospital Patients in Need of Palliative Care Using a New Simplified Screening Tool N/A
Terminated NCT00208078 - Effect of Non-Invasive Ventilation in Cystic Fibrosis Patient With Chronic Respiratory Failure. Phase 4
Recruiting NCT06286917 - Initiation of Noninvasive Ventilation in ALS Patients With Chronic Respiratory Insufficiency N/A
Completed NCT02342899 - Cost Effectiveness of Outpatient Set-up of Automated NIV in Obese Patients With Chronic Respiratory Failure Phase 3
Terminated NCT03473171 - Implementation of Nasal Non-Invasive Ventilation With a RAM Cannula in the Inpatient /Outpatient Setting N/A
Not yet recruiting NCT05258370 - Fibroblast Growth Factor 23 in Chronic Respiratory Failure
Completed NCT02804243 - The Efficacy of Nasal High Flow Oxygen Therapy With Rehabilitation in the Patients With Chronic Respiratory Failure N/A
Completed NCT01479959 - Impact of Patient Controlled Positive End-expiratory Pressure on Speech in Tracheostomized Ventilated Patients N/A
Completed NCT01090986 - Home Mechanical Ventilation Effectiveness and Air Leaks N/A
Completed NCT00698958 - Ambulatory Adaptation to Non-Invasive Mechanical Ventilation Phase 4
Not yet recruiting NCT06119087 - Mechanical Insufflation in the Philadelphia Amyotrophic Lateral Sclerosis Cohort (MI-PALS) Study N/A
Recruiting NCT05796297 - Clinical Impact of Patient-ventilator Asynchrony
Recruiting NCT04481295 - Study on Optimal Oxygen Concentration During Pulmonary Rehabilitation N/A
Withdrawn NCT05379439 - Family Connections N/A